Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children

The Pediatric Infectious Disease Journal
Mark P NicolHeather J Zar

Abstract

We determined the accuracy of the new Xpert MTB/RIF Ultra assay for diagnosis of pulmonary tuberculosis in children, using banked-induced sputum. Sensitivity and specificity were 75.3% and 96.9%, respectively, compared with a culture result from the same specimen. Of those children with microbiologically confirmed tuberculosis (positive Xpert, Ultra or culture), Xpert detected 63.2%, Ultra 73.7% and culture 82.9%.

References

Oct 26, 2011·The Journal of Infectious Diseases·Tom G ConnellMark P Nicol
Mar 31, 2015·The Lancet. Respiratory Medicine·Anne K DetjenAnna M Mandalakas
Sep 27, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Stephen M GrahamHeather J Zar

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Citations

Sep 14, 2018·PloS One·Toyin Omotayo TogunMadhukar Pai
Jan 17, 2019·Expert Review of Respiratory Medicine·Jennifer Furin
May 19, 2018·The European Respiratory Journal·Paola VillanuevaUNKNOWN Paediatric Tuberculosis Network European Trials Group
Apr 5, 2019·Journal of Clinical Microbiology·Jerome H ChinWilly Ssengooba
Aug 6, 2019·American Journal of Respiratory and Critical Care Medicine·Heather J ZarMark P Nicol
Feb 25, 2020·Journal of the Pediatric Infectious Diseases Society·Marvah Hill Pierre-LouisPeter F Wright
Aug 28, 2020·The Cochrane Database of Systematic Reviews·Alexander W KayAnna M Mandalakas
Aug 8, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mark P NicolClaudia M Denkinger
Mar 17, 2020·American Journal of Respiratory and Critical Care Medicine·Saurav JainJagdish Prasad Goyal
Jan 27, 2019·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Elisabeth HodilleOana Dumitrescu
Mar 17, 2020·American Journal of Respiratory and Critical Care Medicine·Heather J Zar
Jun 8, 2018·Pneumonia·Rkia Eddabra, Hassan Ait Benhassou
Mar 16, 2019·Frontiers in Pediatrics·Rachel R AthertonDavid R Boulware
Mar 27, 2020·Frontiers in Pediatrics·Samantha H-L FryMark F Cotton
May 7, 2020·Current Opinion in Pediatrics·Annaleise R Howard-Jones, Ben J Marais
May 10, 2018·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Patrick OrikirizaMaryline Bonnet
May 19, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Senjuti KabirSayera Banu
Nov 21, 2020·The European Respiratory Journal·Arnold BainomugisaBen J Marais
Jan 9, 2021·Journal of the Pediatric Infectious Diseases Society·Devan JaganathAdithya Cattamanchi
Nov 23, 2019·The Lancet Child & Adolescent Health·Kathryn J SnowKatharina Kranzer
Dec 10, 2019·The Indian Journal of Tuberculosis·Sangeeta SharmaV P Myneedu
Mar 18, 2021·Infection and Drug Resistance·Luis Horacio Gutiérrez-GonzálezYolanda Gonzalez
Sep 29, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Chunyang LyuYongmei Jiang
Sep 19, 2019·Lancet·Anja ReuterJennifer Furin
Nov 5, 2021·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Xiaoshan PengChaomin Wan
Nov 15, 2021·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Samanta BiswasSayera Banu

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