Accurate and sensitive determination of selected hormones, endocrine disruptors, and pesticides by gas chromatography-mass spectrometry after the multivariate optimization of switchable solvent liquid-phase microextraction

Journal of Separation Science
Dotse Selali ChormeySezgin Bakırdere

Abstract

Switchable solvent liquid-phase microextraction was combined with gas chromatography and mass spectrometry to improve the sensitivity and accuracy for the determination of selected endocrine disruptors, pesticides, and hormones. The extraction method was used to complement gas chromatography with mass spectrometry by preconcentrating analytes for trace determinations. A Box-Behnken experimental design was used to evaluate the main variables and their interaction effects, and optimum parameters were selected based on the model of experimented results. Application of optimum extraction conditions to mixed standard solutions yielded limits of detection and quantitation values between 0.20-13 and 0.90-46 ng/mL, respectively. The accuracy and the applicability of the developed method was checked in tap water and two different wastewater samples by spiked recovery tests. The percent recoveries recorded for the analytes were between 91 and 110%, and percent relative standard deviation values were all below 10%. The results indicate that the method can be used for the accurate and sensitive determination of these analytes in the presented matrixes.

References

Jul 28, 2009·Journal of Hazardous Materials·Hyun-Shik ChangSang-June Choi
Nov 16, 2010·Journal of Separation Science·Yogesh B Pakade, Dhananjay Kumar Tewary
Sep 9, 2011·The Journal of Steroid Biochemistry and Molecular Biology·Thaddeus T SchugJerrold J Heindel
May 11, 2012·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·V C FernandesC Delerue-Matos
Nov 5, 2013·Ecotoxicology and Environmental Safety·Krishna Kumar SelvarajBabu Rajendran Ramaswamy
May 15, 2015·Environment International·Merete GrungThorjørn Larssen
Jul 15, 2015·Environmental Toxicology and Pharmacology·Eva Rahman KabirImon Rahman
Oct 12, 2016·Journal of Analytical Methods in Chemistry·Thamani T GondoHarriet Okatch
Mar 28, 2017·Talanta·Huy NguyenPhilippe Daniel
Nov 12, 2017·Comptes rendus biologies·Claude Monneret

❮ Previous
Next ❯

Citations

Oct 9, 2019·Bulletin of Environmental Contamination and Toxicology·Hanife Sari ErkanSezgin Bakırdere
Jan 1, 2021·Talanta·Herbert Musarurwa, Nikita Tawanda Tavengwa

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved