Accurate CT∕MR vessel-guided nonrigid registration of largely deformed livers

Medical Physics
Eliana M Vásquez OsorioBen J M Heijmen

Abstract

Computer tomography (CT) scans are used for designing radiotherapy treatment plans. However, the tumor is often better visible in magnetic resonance (MR) images. For liver stereotactic body radiation therapy (SBRT), the planning CT scan is acquired while abdominal compression is applied to reduce tumor motion induced by breathing. However, diagnostic MR scans are acquired under voluntary breath-hold without the compression device. The resulting large differences in liver shape hinder the alignment of CT and MR image sets, which severely limits the integration of the information provided by these images. The purpose of the current study is to develop and validate a nonrigid registration method to align breath-hold MR images with abdominal-compressed CT images, using vessels that are automatically segmented within the liver. Contrast-enhanced MR and CT images of seven patients with liver cancer were used for this study. The registration method combines automatic vessel segmentation with an adapted version of thin-plate spline robust point matching. The vessel segmentation uses a multiscale vesselness measure, which allows vessels of various thicknesses to be segmented. The nonrigid registration is point-based, and progressively i...Continue Reading

References

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Citations

May 30, 2014·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·D S YangS H Cha
Jul 15, 2015·IEEE Transactions on Bio-medical Engineering·Caitlin SchneiderSeptimiu Salcudean
Feb 6, 2017·Journal of Medical Imaging·Xishi HuangMark Green
Nov 6, 2018·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jeong Hee YoonJoon Koo Han
Feb 23, 2021·European Journal of Radiology·Jeong Hee YoonKyung-Suk Suh

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