Accurate Determination of Childhood Food Allergy Prevalence and Correction of Unnecessary Avoidance

Allergy, Asthma & Immunology Research
Yuki OkadaAkira Akasawa

Abstract

Because the true prevalence of food allergy (FA), as based on the results of an oral food challenge test (OFC), is unknown, it is likely that children with suspected FA unnecessarily eliminate potentially causative foods. This study aimed to identify the prevalence of FA and to determine the proportion of children who unnecessarily eliminate food. To identify children with FA, a primary survey was conducted via a questionnaire with all children aged 0-18 years in Niijima village (remote islands of Japan). In the secondary survey, a detailed medical interview was conducted by doctors with children who currently did not eat some foods. The third survey involved serum food-specific immunoglobulin E (IgE) tests and an OFC for children with suspected FA. Of 376 enrolled children, 374 (99.5%) completed the questionnaire. Some foods were eliminated by 18.6% and 13.0% of all children and those ≥6 years old, respectively. The target population for the secondary survey included 69 children who all completed the medical interview. The target population for the third survey consisted of 35 children, of whom 26 (74.3%) underwent the blood test. An OFC was performed 35 times with 20 children. As a result, the prevalence of FA was 4.9% in chi...Continue Reading

References

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Oct 8, 2015·Allergy·Annette CarrardC Sokollik

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Citations

Jun 24, 2017·Indian Journal of Pediatrics·Joseph L Mathew
Mar 14, 2019·Expert Review of Clinical Immunology·Alexandra LangloisPhilippe Bégin
Jan 7, 2019·Clinical Reviews in Allergy & Immunology·Rui TangJin-Lyu Sun

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