Abstract
Axillary lymph node enlargement following sentinel lymph node biopsy (SLNB) is often difficult to accurately diagnose. In keeping with the characteristically tortuous and aberrant pattern of tumor neovasculature, metastatic lymph nodes exhibit peripheral and mixed vascularity, resulting in a microvasculature that is often difficult to visualize. Contrast-enhanced ultrasonography (CEUS) with Sonazoid, a new generation contrast agent for ultrasonography, allows for the visualization of lymph node microvessels and may enable a more accurate evaluation of lymph node metastasis. This is a case report of axillary lymph node enlargement following SLNB, in which CEUS with Sonazoid resulted in an accurate diagnosis. On the basis of our experience with this case, we have initiated a clinical trial to evaluate the detection of lymph node metastasis through the use of CEUS in breast cancer patients.
References
Feb 1, 1977·Cancer·R M Cabanas
May 15, 1983·Cancer·J LacourC Hill
Aug 1, 1983·Annals of Surgery·W A MaddoxC M Balch
Apr 6, 1995·The New England Journal of Medicine·J A JacobsonP Okunieff
May 5, 2000·Radiology·W T YangC Metreweli
Sep 21, 2000·European Radiology·K A KvistadO Haraldseth
Oct 24, 2002·The New England Journal of Medicine·Bernard FisherNorman Wolmark
Aug 21, 2004·Annals of Surgery·Arpana M NaikHiram S Cody
Mar 10, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Andrew Quon, Sanjiv S Gambhir
Mar 12, 2005·CA: a Cancer Journal for Clinicians·D Max ParkinPaola Pisani
Sep 15, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Gary H LymanUNKNOWN American Society of Clinical Oncology
Dec 6, 2005·Cancer·Theodore KimGary H Lyman
Oct 10, 2007·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Eun Young KoSeok Seon Kang
May 15, 2008·The Breast Journal·Claudia S MameriSergio Ajzen
May 27, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·T S DabakuyoF Bonnetain
Jun 13, 2009·Ultrasound in Medicine & Biology·Kiyoka OmotoMikihiko Kawano
Feb 9, 2010·Breast Cancer Research and Treatment·Rebecca PeareS D Heys
Dec 15, 2010·Ultrasound in Medicine & Biology·Antonio García FernándezA Pessarrodona
May 21, 2011·Annals of Surgery·Nehmat HoussamiPetra Macaskill
Aug 23, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S E HarnanL Wyld
Jan 10, 2012·World Journal of Radiology·Takaya AokiYasuharu Imai
Jan 10, 2012·Annals of Surgical Oncology·Stephanie A ValenteStephen F Sener
Oct 25, 2013·Journal of breast cancer·Seung Ook HwangJin Hyang Jung
Citations
Sep 26, 2015·SpringerPlus·Fumihiko MatsuzawaKenichi Kyuno
Oct 5, 2018·The Laryngoscope·Caitlin BertelsenJon-Paul Pepper
Feb 7, 2018·BMC Cancer·Jerica NovakAndrej Vogrin
Mar 16, 2018·Oncology Letters·Shin-Ichi OikawaTamotsu Sugai
Jan 21, 2017·Experimental and Therapeutic Medicine·Minoru TomizawaNaoki Ishige
Oct 30, 2019·Annals of Surgical Oncology·Enqi QiaoHongjian Yang
Apr 15, 2016·Journal of the Belgian Society of Radiology·Nurdan FidanBaki Hekimoglu
Feb 28, 2019·Contrast Media & Molecular Imaging·Xuelei MaJialing He
Aug 27, 2019·American Journal of Veterinary Research·Jaewoo HwangMincheol Choi
Jun 4, 2020·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·H XuC Z Dong
Jan 21, 2021·Medicine·Lu ZhangHui Zhu
Mar 15, 2021·Ultrasound in Medicine & Biology·Yan-Bing LiuYun-Ling Li
Apr 1, 2021·Medicine·Shihui MaFeihai Ling
Jul 10, 2021·Archives of Gynecology and Obstetrics·Xiaojiang WangXiufeng Wu