PMID: 11929015Apr 4, 2002Paper

Accurate localization of intracavitary brachytherapy applicators from 3D CT imaging studies

Medical Physics
F A Lerma, Jeffrey F Williamson

Abstract

To present an accurate method to identify the positions and orientations of intracavitary (ICT) brachytherapy applicators imaged in 3D CT scans, in support of Monte Carlo photon-transport simulations, enabling accurate dose modeling in the presence of applicator shielding and interapplicator attenuation. The method consists of finding the transformation that maximizes the coincidence between the known 3D shapes of each applicator component (colpostats and tandem) with the volume defined by contours of the corresponding surface on each CT slice. We use this technique to localize Fletcher-Suit CT-compatible applicators for three cervix cancer patients using post-implant CT examinations (3 mm slice thickness and separation). Dose distributions in 1-to-1 registration with the underlying CT anatomy are derived from 3D Monte Carlo photon-transport simulations incorporating each applicator's internal geometry (source encapsulation, high-density shields, and applicator body) oriented in relation to the dose matrix according to the measured localization transformations. The precision and accuracy of our localization method are assessed using CT scans, in which the positions and orientations of dense rods and spheres (in a precision-mach...Continue Reading

References

May 1, 1992·Medical Physics·Z Li, J F Williamson
Jul 1, 1990·International Journal of Radiation Oncology, Biology, Physics·J F Williamson
Oct 1, 1987·International Journal of Radiation Oncology, Biology, Physics·C C LingC C Rogers
Nov 1, 1986·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R D HunterJ Wilkinson
Jan 1, 1994·International Journal of Radiation Oncology, Biology, Physics·S L SchoeppelJ A Roberts
Jan 15, 1997·International Journal of Radiation Oncology, Biology, Physics·K J Weeks, G S Montana

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Citations

Mar 15, 2011·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Lan JiangJames C H Chu
Oct 10, 2006·IEEE Transactions on Medical Imaging·Ryan J MurphyJeffrey F Williamson
Nov 4, 2008·Medical Physics·Bruce R ThomadsenAli S Meigooni
Oct 19, 2006·Physics in Medicine and Biology·Donald L SnyderJeffrey F Williamson
Jul 23, 2019·Medical Physics·William T HrinivichJunghoon Lee
Apr 14, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Paul N FiorilliJohn W Hirshfeld

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