Accurate method for clinical assessment of right lobe liver weight in adult living-related liver transplant

Transplantation Proceedings
G E GondolesiS Emre

Abstract

Prior to transplantation of segmental liver grafts to adult recipients, it is crucial to confirm that the graft size is safe for the donor, yet adequate for the recipient's metabolic needs. Computed tomography (CT) and magnetic resonance imaging (MRI) are the current best standards. We applied a new formula to estimate right liver lobe weight in living donors and compared our results with CT and MRI. Between August 1998 and December 20, 91 adults received right lobes from living donors. Donor liver volumes were assessed by CT or MRI. Actual weights of right lobe grafts were determined after back table flushing. We estimated whole liver weights using the formula: 772 x body surface area (BSA). Right lobe liver weight was calculated as 57% of the estimated whole liver weight (R-57). Mean actual right lobe weight (n = 90) was 855.83 +/- 183.4 g. Estimated right lobe weight was 858.08 +/- 90.80 (R-57, P = NS); 1077.35 +/- 263.07 mL for CT (P = .0001), and 1185.07 +/- 350.10 mL for MRI (P = .0001). Mean graft-recipient weight ratio (GRWR) was 1.23%; there was no significant difference with R-57 GRWR but there was a difference from CT and MRI-GRWR (P = .001). The proportion of cases of estimated right lobe weight and GRWR within 20% ...Continue Reading

References

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Citations

Feb 10, 2007·Seminars in Nuclear Medicine·Drew A Torigian, Abass Alavi
Jan 19, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A RadtkeM Malagó
Jan 10, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·A TongyooJ J Pomposelli
Mar 30, 2011·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Frank WangWei-Chen Lee
Jul 23, 2014·Pathology International·Kunihiro InaiHironobu Naiki
Oct 7, 2005·Clinics in Liver Disease·Lawrence U Liu, Thomas D Schiano
Oct 31, 2015·Clinics and Research in Hepatology and Gastroenterology·Mohammad GolrizArianeb Mehrabi
Nov 30, 2005·Transplantation·Paolo R O SalvalaggioMichael M Abecassis
Mar 24, 2006·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Sander Florman, Charles M Miller
May 11, 2017·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Rafael S PinheiroLuiz A C D Albuquerque
Jan 16, 2010·Revista do Colégio Brasileiro de Cirurgiões·Fábio Augusto de CarvalhoJorge Eduardo Fouto Matias

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