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Accurate whole human genome sequencing using reversible terminator chemistry

Nature

Nov 6, 2008

David R. BentleyAnthony James Smith

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Abstract

DNA sequence information underpins genetic research, enabling discoveries of important biological or medical benefit. Sequencing projects have traditionally used long (400-800 base pair) reads, but the existence of reference sequences for the human and many other genomes makes it possib...read more

Mentioned in this Paper

Base Sequence
Deoxyribonucleotides
Genome
Genome, Human
Nucleotides
Genetic Polymorphism
Statistical Sensitivity
X Chromosome
Consensus Sequence
DNA Sequence
9
1
3220
6
Paper Details
References

Accurate whole human genome sequencing using reversible terminator chemistry

Nature

Nov 6, 2008

David R. BentleyAnthony James Smith

PMID: 18987734

DOI: 10.1038/nature07517

Abstract

DNA sequence information underpins genetic research, enabling discoveries of important biological or medical benefit. Sequencing projects have traditionally used long (400-800 base pair) reads, but the existence of reference sequences for the human and many other genomes makes it possib...read more

Mentioned in this Paper

Base Sequence
Deoxyribonucleotides
Genome
Genome, Human
Nucleotides
9
1
3220
6
Paper Details
References

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