Acetic acid improves identification of remnant islands of Barrett's epithelium after endoscopic therapy

Gastrointestinal Endoscopy
M Guelrud, I Herrera

Abstract

Instillation of acetic acid onto the uterine cervix at colposcopy has been used for many years to highlight dysplastic areas and thereby enhance the ability to obtain targeted biopsy specimens. As part of an ongoing trial of multipolar electrocoagulation for Barrett's esophagus, we sought to develop a simple technique to identify small islands of residual specialized columnar epithelium after treatment. In 21 consecutive patients, 5 to 10 mL of 1.5% acetic acid was sprayed onto the distal esophagus using a spray catheter, followed immediately by spraying 50 mL of tap water. Initially, a whitish coloration developed in both esophageal and gastric epithelia. After 2 to 3 minutes, the esophageal squamous mucosa remained white but the columnar epithelium became reddish. Remnant islands of Barrett's epithelium were outlined by a white rim. Acetic acid instillation enhances the ability to detect small or indistinguishable remnant islands of columnar epithelium after endoscopic treatment of Barrett's esophagus. This method is safe, rapid, and inexpensive.

References

Sep 1, 1992·Gastrointestinal Endoscopy·L J Brandt, D R Kauvar
Sep 1, 1996·Obstetrics and Gynecology·E MegevandB Bloch
Jul 1, 1996·Gastrointestinal Endoscopy·M I CantoM V Sivak

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Citations

Jan 15, 2004·Gastrointestinal Endoscopy·Moises Guelrud, Elissa E Ehrlich
Mar 11, 2005·Gastrointestinal Endoscopy·Prateek Sharma
Oct 16, 2008·Journal of Gastroenterology and Hepatology·Toshiro IizukaNaohisa Yahagi
May 6, 2011·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Rajvinder SinghYasser Maqbool Bhat
Apr 12, 2012·World Journal of Gastroenterology : WJG·Ning-Li ChaiBen-Yan Wu
Jul 21, 2004·Gastrointestinal Endoscopy Clinics of North America·Moises Guelrud, Elissa E Ehrlich
May 11, 1999·The American Journal of Gastroenterology·J van den BoogertH W Tilanus
Apr 19, 2006·Gastroenterology·Michael B WallaceUNKNOWN AITGN Symposium Faculty
Oct 22, 2015·Gastroenterology Report·Ajaypal Singh, Amitabh Chak
Jun 15, 2017·Nature Reviews. Gastroenterology & Hepatology·Arthur HoffmanRalf Kiesslich
Apr 2, 2002·The American Journal of Gastroenterology·Moises GuelrudDonald A Antonioli
Jan 13, 2000·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·S J WalkerN Birbeck
Jul 26, 2006·The American Journal of Gastroenterology·Dawn D FergusonMichael B Wallace
Apr 24, 2014·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Kenichi GodaHisao Tajiri
Jan 7, 2017·World Journal of Gastroenterology : WJG·Richard P T EvansSimon R Bramhall
Feb 16, 2007·European Journal of Gastroenterology & Hepatology·José L Vázquez-IglesiasMaría J Lorenzo
Sep 29, 2011·Annals of the New York Academy of Sciences·Norihisa IshimuraRam Chuttani
Feb 1, 2005·Archives of Pathology & Laboratory Medicine·Elizabeth R Tschanz
Nov 26, 2008·Gastroenterology Clinics of North America·Elizabeth L Bird-Lieberman, Rebecca C Fitzgerald
Mar 8, 2011·Gastroenterology·Stuart J SpechlerUNKNOWN American Gastroenterological Association

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