Achieving biopolymer synergy in systems chemistry

Chemical Society Reviews
Yushi BaiD G Lynn

Abstract

Synthetic and materials chemistry initiatives have enabled the translation of the macromolecular functions of biology into synthetic frameworks. These explorations into alternative chemistries of life attempt to capture the versatile functionality and adaptability of biopolymers in new orthogonal scaffolds. Information storage and transfer, however, so beautifully represented in the central dogma of biology, require multiple components functioning synergistically. Over a single decade, the emerging field of systems chemistry has begun to catalyze the construction of mutualistic biopolymer networks, and this review begins with the foundational small-molecule-based dynamic chemical networks and peptide amyloid-based dynamic physical networks on which this effort builds. The approach both contextualizes the versatile approaches that have been developed to enrich chemical information in synthetic networks and highlights the properties of amyloids as potential alternative genetic elements. The successful integration of both chemical and physical networks through β-sheet assisted replication processes further informs the synergistic potential of these networks. Inspired by the cooperative synergies of nucleic acids and proteins in bi...Continue Reading

References

May 19, 1994·Nature·D Sievers, G von Kiedrowski
Jun 26, 1999·Science·A Eschenmoser
Mar 17, 2001·Nature Reviews. Molecular Cell Biology·H Kornberg
Jan 31, 2002·Journal of the American Chemical Society·Xiaoyu LiDavid G Lynn
Jul 18, 2002·Nature Reviews. Drug Discovery·Olof Ramström, Jean-Marie Lehn
May 29, 2004·Science·Kelly S ChichakJ Fraser Stoddart
Jul 17, 2004·Proceedings of the National Academy of Sciences of the United States of America·Gonen AshkenasyM Reza Ghadiri
Dec 15, 2005·Chemical Communications : Chem Comm·Adina N LazarPeter Strazewski
Mar 16, 2006·Journal of the American Chemical Society·Jijun DongDavid G Lynn
Sep 14, 2006·Chemical Reviews·Peter T CorbettSijbren Otto
Sep 15, 2007·Journal of the American Chemical Society·Mustafa O Guler, Samuel I Stupp
Jul 3, 2008·Journal of the American Chemical Society·Anil K MehtaDavid G Lynn
Jul 10, 2008·Angewandte Chemie·Zehavit DadonGonen Ashkenasy
Sep 2, 2008·Biochemistry·Yan LiangDavid G Lynn
Dec 6, 2008·Chemical Communications : Chem Comm·Yan LiangDavid G Lynn
Jan 3, 2009·Nature Nanotechnology·Richard J WilliamsRein V Ulijn
Jan 10, 2009·Science·Tracey A Lincoln, Gerald F Joyce
Jun 13, 2009·Science·Yasuyuki UraM Reza Ghadiri
Aug 1, 2009·Angewandte Chemie·Boris RubinovGonen Ashkenasy
Dec 17, 2009·Nature·Jonathan R Nitschke
Mar 20, 2010·Science·Jacqui M A CarnallSijbren Otto
Apr 20, 2010·Journal of the American Chemical Society·Yan LiangKeith M Berland
Oct 16, 2010·Structure·Jason Greenwald, Roland Riek
Dec 15, 2010·Chemical Society Reviews·Hana Robson MarsdenAlexander Kros
Apr 22, 2011·Current Opinion in Chemical Biology·Monica C BrancoJoel P Schneider
Aug 24, 2011·Nature Chemistry·Jason E HeinDonna G Blackmond
Sep 6, 2011·Chemical Communications : Chem Comm·Zehavit DadonGonen Ashkenasy
Nov 15, 2011·Chemical Communications : Chem Comm·John B Matson, Samuel I Stupp
Nov 26, 2011·Nanoscale·Mordechay MizrahiNurit Ashkenasy
Mar 24, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·W Seth ChildersDavid G Lynn
May 24, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Rahau S ShiraziCyrus R Safinya
Jun 28, 2012·Angewandte Chemie·Rong NiDavid G Lynn
Aug 4, 2012·ACS Nano·Boris RubinovGonen Ashkenasy
Oct 27, 2012·Accounts of Chemical Research·Jay T GoodwinDavid G Lynn
Dec 21, 2012·Chembiochem : a European Journal of Chemical Biology·Rafał WieczorekPierre-Alain Monnard
Mar 13, 2013·Accounts of Chemical Research·John D Tovar
Apr 12, 2013·Journal of the American Chemical Society·Yves RuffSamuel I Stupp
Jun 5, 2013·Journal of the American Chemical Society·Jianwei LiSijbren Otto
Oct 16, 2013·Angewandte Chemie·Andrew J Bissette, Stephen P Fletcher
Nov 1, 2013·Chemical Reviews·Kepa Ruiz-MirazoAndrés de la Escosura

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Citations

Nov 16, 2019·Chemistry : a European Journal·Sara Morales-ReinaAndrés de la Escosura
May 20, 2020·Chemistry : a European Journal·Fredrik SchaufelbergerOlof Ramström
Aug 3, 2019·Life·Peter Strazewski
Nov 21, 2018·Journal of Molecular Evolution·Calvin M RunnelsLoren Dean Williams
Aug 19, 2020·Nature Chemistry·Helena S AzevedoDibyendu Das
Feb 13, 2020·Protein and Peptide Letters·Yu ChenEhud Gazit
Feb 25, 2021·Proceedings of the National Academy of Sciences of the United States of America·Anil Kumar BandelaGonen Ashkenasy
Feb 27, 2020·Chemical Reviews·Moran Frenkel-PinterLuke J Leman
Apr 18, 2021·Colloids and Surfaces. B, Biointerfaces·Avigail Baruch-LeshemHanna Rapaport
Jun 25, 2021·Chemical Science·Junjun TanDavid G Lynn
Dec 17, 2020·Journal of the American Chemical Society·Liang YueItamar Willner
Sep 15, 2021·Chemical Reviews·Fahmeed SheehanRein V Ulijn
Sep 21, 2021·Chemical Society Reviews·Amit KahanaDoron Lancet
Oct 16, 2021·Journal of the American Chemical Society·Chiara GlionnaNurit Ashkenasy
Nov 13, 2021·Angewandte Chemie·Sumit PalDibyendu Das
Jan 7, 2022·Journal of the American Chemical Society·Syed Pavel AfroseDibyendu Das

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Methods Mentioned

BETA
peptide folding
protein folding
AFM
chip
fluorescence imaging
transfection

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