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Achieving large dynamic range control of gene expression with a compact RNA transcription-translation regulator

Nucleic Acids Research

May 19, 2017

Alexandra M Westbrook, Julius B. Lucks

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Abstract

RNA transcriptional regulators are emerging as versatile components for genetic network construction. However, these regulators suffer from incomplete repression in their OFF state, making their dynamic range less than that of their protein counterparts. This incomplete repression cause...read more

Mentioned in this Paper

Gene Expression
DNA Sequence
Protein Biosynthesis
Transcriptional Regulation
Primary RNA Transcript
Ridges-off-the-end Syndrome
Moving
RNA
Transcription Termination
Site
23
45
Paper Details
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Achieving large dynamic range control of gene expression with a compact RNA transcription-translation regulator

Nucleic Acids Research

May 19, 2017

Alexandra M Westbrook, Julius B. Lucks

PMID: 28387839

DOI: 10.1093/nar/gkx215

Abstract

RNA transcriptional regulators are emerging as versatile components for genetic network construction. However, these regulators suffer from incomplete repression in their OFF state, making their dynamic range less than that of their protein counterparts. This incomplete repression cause...read more

Mentioned in this Paper

Gene Expression
DNA Sequence
Protein Biosynthesis
Transcriptional Regulation
Primary RNA Transcript
23
45

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