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Achieving large dynamic range control of gene expression with a compact RNA transcription-translation regulator

bioRxiv

May 24, 2016

Alexandra M Westbrook, Julius B Lucks

Abstract

RNA transcriptional regulators are emerging as versatile components for genetic circuit construction. However, RNA transcriptional regulators suffer from incomplete repression, making their dynamic range less than that of their protein counterparts. This incomplete repression can cause ...read more

Mentioned in this Paper

In Vivo
Transcriptional Regulation
Roberts-SC Phocomelia Syndrome
Primary RNA Transcript
Regulation of Biological Process
Transcription Termination
Transcription, Genetic
Antisense RNA
Protein Biosynthesis
Gene Expression
4
13
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Achieving large dynamic range control of gene expression with a compact RNA transcription-translation regulator

bioRxiv

May 24, 2016

Alexandra M Westbrook, Julius B Lucks

PMID: 990055327

DOI: 10.1101/055327

Abstract

RNA transcriptional regulators are emerging as versatile components for genetic circuit construction. However, RNA transcriptional regulators suffer from incomplete repression, making their dynamic range less than that of their protein counterparts. This incomplete repression can cause ...read more

Mentioned in this Paper

In Vivo
Transcriptional Regulation
Roberts-SC Phocomelia Syndrome
Primary RNA Transcript
Regulation of Biological Process
Transcription Termination
Transcription, Genetic
Antisense RNA
Protein Biosynthesis
Gene Expression
4
13

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