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Achieving large dynamic range control of gene expression with a compact RNA transcription-translation regulator

bioRxiv

May 24, 2016

Alexandra M Westbrook, Julius B. Lucks

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Abstract

RNA transcriptional regulators are emerging as versatile components for genetic circuit construction. However, RNA transcriptional regulators suffer from incomplete repression, making their dynamic range less than that of their protein counterparts. This incomplete repression can cause ...read more

Mentioned in this Paper

Gene Expression
Small Molecule
Protein Biosynthesis
Transcriptional Regulation
Roberts-SC Phocomelia Syndrome
Primary RNA Transcript
Moving
RNA
Transcription Termination
Antisense RNA Location
4
20
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  • Achieving large dynamic range control of gene expression with a compact RNA transcription-translation regulator

    bioRxiv

    May 24, 2016

    Alexandra M Westbrook, Julius B. Lucks

    PMID: 990055327

    DOI: 10.1101/055327

    Abstract

    RNA transcriptional regulators are emerging as versatile components for genetic circuit construction. However, RNA transcriptional regulators suffer from incomplete repression, making their dynamic range less than that of their protein counterparts. This incomplete repression can cause ...read more

    Mentioned in this Paper

    Gene Expression
    Small Molecule
    Protein Biosynthesis
    Transcriptional Regulation
    Roberts-SC Phocomelia Syndrome
    4
    20

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