Achieving Reliable Diagnosis in Late Breast Implant Seromas: From Reactive to Anaplastic Large Cell Lymphoma

Plastic and Reconstructive Surgery
Arianna Di Napoli

Abstract

Late onset of fluid collection surrounding breast implants may represent a serious issue when considering the possibility of breast implant-associated anaplastic large cell lymphoma, a newly recognized type of T-cell malignancy. However, many other factors, including trauma and infections, may be implicated in the formation of non-neoplastic periprosthetic delayed effusions. An appropriate management of late seromas, consisting of ultrasound-guided fluid drainage, cultures, cytology, and immunocytochemical and T-cell clonality studies, should be performed to achieve a correct and prompt diagnosis of breast implant-associated anaplastic large cell lymphoma. Criticisms in the diagnosis of late peri-implant effusions are here discussed in detail.

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Citations

Jun 27, 2020·Plastic and Reconstructive Surgery·Erica LeeJustin M Sacks
Dec 29, 2019·Plastic and Reconstructive Surgery·Maurice Y Nahabedian
Nov 2, 2020·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Francesco VerdeMassimo Imbriaco
Apr 24, 2021·Plastic and Reconstructive Surgery·Amy S ColwellMichelle C Specht
Apr 24, 2021·Plastic and Reconstructive Surgery·Malke AsaadMark W Clemens
Feb 10, 2021·Annals of Plastic Surgery·Gorka IbarraAngela Garcia-Ruano

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