Achieving target levels for vascular risk parameters in Polish school-age children with type 1 diabetes - a single center study

Journal of Pediatric Endocrinology & Metabolism : JPEM
Agnieszka SzadkowskaBeata Mianowska

Abstract

Background Therapeutic goals have been established to decrease the risk of long-term complications of type 1 diabetes (T1DM). The effects of these guidelines should be constantly evaluated. Hence, the present study examines the frequency at which children with T1DM treated by one of the Polish reference centers complied with the therapeutic targets issued in 2014 by the International Society for Pediatric and Adolescent Diabetes (ISPAD) and by the Diabetes Poland (PTD). Methods A retrospective analysis (years 2011-2014) was performed in patients with T1DM aged 6.5-18 years, with diabetes duration >12 months and no change of insulin regimen within 6 months. Collected data included insulin therapy regimen, weight, height, blood pressure, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG) and glycated hemoglobin (HbA1c) level from the last hospitalization. Results The records of 447 patients (260 boys, 299 treated with insulin pump) were analyzed. All ISPAD goals were achieved by 123 (27.5%) patients, but only 43 (9.6%) met all PTD targets. Optimal HbA1c was achieved by 224 (50.1%) according to ISPAD criteria (HbA1c<7.5%) and by 87 (19.6%) patients according to PTD (HbA1c≤...Continue Reading

References

Dec 6, 2003·The Journal of Pediatrics·Steven M WilliSharon Schwarz
Sep 2, 2006·BMJ : British Medical Journal·Sally M Marshall, Allan Flyvbjerg
Jan 16, 2009·Diabetes/metabolism Research and Reviews·Swapnil N RajpathakHoward D Strickler
Feb 11, 2012·Journal of Internal Medicine·M Laakso, H Cederberg
May 1, 2013·Pediatric Diabetes·F J CameronUNKNOWN Hvidoere International Study Group
Nov 8, 2013·Journal of Pediatric Endocrinology & Metabolism : JPEM·Thomas M KapellenUNKNOWN DPV-Science-Initiative of the German Competence Network Diabetes and the German Competence Network Obesity (Consortium LARGE
May 16, 2014·Diabetes/metabolism Research and Reviews·Orit Pinhas-HamielRachel Frumkin Ben-David
Jan 1, 2015·Journal of Diabetes and Metabolic Disorders·Nadia MahdadMalika Bouchenak
Mar 17, 2015·Journal of Diabetes and Its Complications·Vincenzo LaganiIoannis Tsamardinos
Jul 15, 2015·Pediatric Diabetes·Mark A ClementsUNKNOWN T1D Exchange Clinic Network
Jul 15, 2015·The Journal of Pediatrics·Stephanie N DuBoseUNKNOWN Type 1 Diabetes Exchange Clinic Network and Diabetes Prospective Follow-up Registry
Jul 16, 2016·Pediatric Diabetes·Agnieszka SzypowskaUNKNOWN SWEET Study Group
Dec 21, 2016·Journal of Pediatric Endocrinology & Metabolism : JPEM·Tuba BulutAyşe Metin
Mar 4, 2017·Diabetic Medicine : a Journal of the British Diabetic Association·A ChobotP Jarosz-Chobot
Oct 27, 2017·Pediatric endocrinology, diabetes, and metabolism·Honorata KołodziejczykMieczysław Szalecki

❮ Previous
Next ❯

Citations

Aug 15, 2020·Frontiers in Endocrinology·Barbara Głowinska-OlszewskaArtur Bossowski

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

ApoE, Lipids & Cholesterol

Serum cholesterol, triglycerides, apolipoprotein B (APOB)-containing lipoproteins (very low-density lipoprotein (VLDL), immediate-density lipoprotein (IDL), and low-density lipoprotein (LDL), lipoprotein A (LPA)) and the total cholesterol/high-density lipoprotein (HDL) cholesterol ratio are all connected in diseases. Here is the latest research.

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.

Cardiovascular Disorder in Diabetes

Diabetes is associated with an increased risk of cardiovascular disorders and heart failure. Discover the latest research here.