Acid-base regulation in the plainfin midshipman (Porichthys notatus): an aglomerular marine teleost

Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
Steve F PerryK M Gilmour

Abstract

The plainfin midshipman (Porichthys notatus) possesses an aglomerular kidney and like other marine teleosts, secretes base into the intestine to aid water absorption. Each of these features could potentially influence acid-base regulation during respiratory acidosis either by facilitating or constraining HCO(3)(-) accumulation, respectively. Thus, in the present study, we evaluated the capacity of P. notatus to regulate blood acid-base status during exposure to increasing levels of hypercapnia (nominally 1-5% CO(2)). Fish exhibited a well-developed ability to increase plasma HCO(3)(-) levels with values of 39.8 ± 2.8 mmol l(-1) being achieved at the most severe stage of hypercapnic exposure (arterial blood PCO(2) = 21.9 ± 1.7 mmHg). Consequently, blood pH, while lowered by 0.15 units (pH = 7.63 ± 0.06) during the final step of hypercapnia, was regulated far above values predicted by chemical buffering (predicted pH = 7.0). The accumulation of plasma HCO(3)(-) during hypercapnia was associated with marked increases in branchial net acid excretion (J (NET)H(+)) owing exclusively to increases in the titratable alkalinity component; total ammonia excretion was actually reduced during hypercapnia. The increase in J (NET)H(+) was acc...Continue Reading

References

May 15, 2012·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Andrew J EsbaughM Grosell
Jun 14, 2013·Proceedings. Biological Sciences·Martin TresguerresGreg W Rouse
Dec 22, 2015·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Katharina MichaelMagnus Lucassen
Aug 21, 2012·Physiological and Biochemical Zoology : PBZ·Rachael M HeuerM Grosell
Feb 19, 2013·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Yung-Che TsengPung-Pung Hwang
Sep 30, 2016·Scientific Reports·Rachael M Heuer, M Grosell
May 27, 2017·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Andrew J Esbaugh
Mar 6, 2016·The Journal of Experimental Biology·Brittany E DavisAnne E Todgham
Aug 29, 2014·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Rachael M Heuer, M Grosell

Citations

Mar 1, 1976·The American Journal of Physiology·D J RandallF Drees
Apr 1, 1978·Respiration Physiology·J N Cameron
Aug 15, 1992·The Journal of Experimental Zoology·G G GossP Laurent
Feb 11, 1969·The American Journal of Physiology·C E CrossE D Robin
Jul 13, 2002·The Journal of Experimental Zoology·James B ClaiborneAlison I Morrison-Shetlar
Nov 22, 2002·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·M Danielle McDonaldC M Wood
Apr 19, 2003·The Journal of Experimental Biology·D J McKenzieJ F Steffensen
Nov 5, 2003·Journal of Experimental Zoology. Part A, Comparative Experimental Biology·S F PerryS L Y Thomas
Jan 15, 2004·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Hidekazu TohseYasuo Mugiya
Apr 13, 2004·American Journal of Physiology. Renal Physiology·Klaus W Beyenbach
Jan 21, 2006·The Journal of Experimental Biology·T GeorgalisK M Gilmour
Mar 31, 2006·American Journal of Physiology. Cell Physiology·Yong-Fu XiaoDaniel C Sigg
May 20, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·M Grosell, J Genz
Jun 17, 2006·Respiratory Physiology & Neurobiology·S F Perry, K M Gilmour
Jul 22, 2006·The Journal of Experimental Biology·M Grosell
Sep 25, 2007·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·M Danielle McDonald, P J Walsh
Sep 19, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Katrin DeigweiherMagnus Lucassen
Jan 20, 2009·Science·R W WilsonM Grosell
Apr 3, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·D W BakerC J Brauner
May 19, 2009·The Journal of Experimental Biology·K M Gilmour, S F Perry

Related Concepts

Pissodes notatus
Carbonic Acid Ions
Kidney
Process of Secretion
Acidosis, Respiratory
Gases, Blood, pH Only
Hypercapnia
Intestinal Wall Tissue
Blood Ammonia Measurement
Body Excretions

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Related Papers

Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology
Andrew J EsbaughM Grosell
Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
G SattinM Grosell
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Katrin DeigweiherMagnus Lucassen
© 2020 Meta ULC. All rights reserved