PMID: 6988937Jan 1, 1980Paper

Acid response to sham feeding as a test for completeness of vagotomy

Scandinavian Journal of Gastroenterology
O Kronborg, D Andersen


The reproducibility of acid responses to modified sham feeding by the chew-and-spit technique (PAOsh) was investigated in 21 duodenal ulcer (DU) patients 8 to 14 days after vagotomy. Possible relationships between PAOsh and the acid response to 0.2 U of insulin per kilogram body weight were examined (PAOI) in 23 other DU patients 8 to 14 days after vagotomy. PAOsh was reproducible to a high degree (PSpearman less than 0.001, CV 2.9%), and a highly significant relationship was found between PAOsh and PAOI after vagotomy (PSp less than 0.001). PAOsh and PAOI were similar when PAOI was low, whereas a highly incomplete vagotomy according to PAOI was followed by a somewhat lower, but substantial, acid response to sham feeding. The relationship between PAOsh and PAOI permits the recommendation of modified sham feeding as a safe stimulant of acid secretion in quantitative testing of completeness of vagotomy.


Oct 1, 1983·Journal of the Autonomic Nervous System·L OlbeB Stenquist
Mar 1, 1993·Baillière's Clinical Gastroenterology·R E Pounder, A G Fraser
Jan 13, 2000·Alimentary Pharmacology & Therapeutics·D C Metz, J A Starr
Jan 1, 1981·Scandinavian Journal of Gastroenterology·O Kronborg
Apr 1, 1990·The British Journal of Surgery·C D Johnson, A S Rai
Feb 1, 1986·The British Journal of Surgery·A C AthowC G Clark
Aug 23, 2002·Annals of Surgery·Farzaneh BankiTom R DeMeester

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Duodenal Ulcer
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