Acidic cell elongation drives cell differentiation in the Arabidopsis root

The EMBO Journal
Elena PacificiSabrina Sabatini

Abstract

In multicellular systems, the control of cell size is fundamental in regulating the development and growth of the different organs and of the whole organism. In most systems, major changes in cell size can be observed during differentiation processes where cells change their volume to adapt their shape to their final function. How relevant changes in cell volume are in driving the differentiation program is a long-standing fundamental question in developmental biology. In the Arabidopsis root meristem, characteristic changes in the size of the distal meristematic cells identify cells that initiated the differentiation program. Here, we show that changes in cell size are essential for the initial steps of cell differentiation and that these changes depend on the concomitant activation by the plant hormone cytokinin of the EXPAs proteins and the AHA1 and AHA2 proton pumps. These findings identify a growth module that builds on a synergy between cytokinin-dependent pH modification and wall remodeling to drive differentiation through the mechanical control of cell walls.

References

Mar 9, 1999·The Plant Journal : for Cell and Molecular Biology·S J Clough, A F Bent
Aug 10, 2000·Proceedings of the National Academy of Sciences of the United States of America·H T Cho, D J Cosgrove
Dec 5, 2000·Current Biology : CB·P N Benfey, B Scheres
Feb 6, 2003·Genes & Development·Sabrina SabatiniBen Scheres
Jun 14, 2003·Plant Physiology·Ivan BaxterKristian B Axelsen
Nov 2, 2005·Nature Reviews. Molecular Cell Biology·Daniel J Cosgrove
Dec 17, 2005·Genome Biology·Javier Sampedro, Daniel J Cosgrove
Mar 17, 2007·Current Biology : CB·Raffaele Dello IoioSabrina Sabatini
Dec 7, 2007·Current Opinion in Plant Biology·Raffaele Dello IoioSabrina Sabatini
Mar 30, 2010·The Journal of Biological Chemistry·Miyoshi HarutaMichael R Sussman
Aug 25, 2010·Methods in Molecular Biology·Serena Perilli, Sabrina Sabatini
Jan 29, 2011·Development·Yael HachamSigal Savaldi-Goldstein
Oct 9, 2012·Current Biology : CB·Bojan GujasChristian S Hardtke
Dec 18, 2012·BMC Biology·Wallace F MarshallAdrienne H K Roeder
Apr 17, 2014·Genes & Development·Yulia FridmanSigal Savaldi-Goldstein
Jan 30, 2015·Journal of Experimental Botany·Elena PacificiSabrina Sabatini
Oct 18, 2015·Current Opinion in Plant Biology·Miyoshi HarutaMichael R Sussman
May 7, 2016·Science Advances·Jérémy GruelHenrik Jönsson
Aug 24, 2017·Proceedings of the National Academy of Sciences of the United States of America·Riccardo Di MambroSabrina Sabatini

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Citations

Feb 13, 2019·The Plant Journal : for Cell and Molecular Biology·Jan SkalákBřetislav Brzobohatý
Apr 11, 2019·Plants·Emanuela PierdonatiRiccardo Di Mambro
Feb 23, 2019·Scientific Reports·Camille Fonouni-FardeFlorian Frugier
Nov 16, 2019·Plant & Cell Physiology·Pamela A NaulinRodrigo A Gutiérrez
Feb 18, 2020·Journal of Experimental Botany·Elena SalviSabrina Sabatini
Apr 5, 2019·Proceedings of the National Academy of Sciences of the United States of America·Priya RamakrishnaIve De Smet
Aug 7, 2019·The Plant Journal : for Cell and Molecular Biology·Judith BäumlerAngelika Mustroph
Jan 4, 2019·Plants·Riccardo Di MambroRaffaele Dello Ioio
Nov 19, 2020·Proceedings. Biological Sciences·Kirsten Bomblies
Feb 20, 2021·Proceedings of the National Academy of Sciences of the United States of America·Annalisa RizzaAlexander M Jones
May 6, 2021·International Journal of Molecular Sciences·Jacob P Rutten, Kirsten H Ten Tusscher
May 14, 2021·Frontiers in Plant Science·Estephania Zluhan-MartínezAdriana Garay-Arroyo
May 20, 2020·Developmental Cell·Tom Bennett
Jun 2, 2021·Horticulture Research·Wenqi WuHairong Wei
Aug 4, 2021·Journal of Experimental Botany·Amel YamouneJan Hejatko
Aug 6, 2021·Journal of Experimental Botany·Gaia BertolottiRaffaele Dello Ioio
May 19, 2021·Cold Spring Harbor Perspectives in Biology·Jaap RuttenKirsten Ten Tusscher

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