Acinetobacter chinensis, a novel Acinetobacter species, carrying blaNDM-1 , recovered from hospital sewage

The Journal of Microbiology
Yiyi HuZhiyong Zong

Abstract

Two strains of the genus Acinetobacter, named WCHAc010005 and WCHAc010052, were isolated from hospital sewage at West China Hospital in Chengdu, China. The two strains were found to be resistant to carbapenems due to the presence of carbapenemase gene blaNDM-1. Based on the comparative analysis of the rpoB sequence, the two strains formed a strongly supported and internally coherent cluster (intracluster identity of 98.7%), which was clearly separated from all known Acinetobacter species (≤ 83.4%). The two strains also formed a tight and distinct cluster based on the genuswide comparison of whole-cell mass fingerprints generated by MALDI-TOF mass spectrometry. In addition, the combination of their ability to assimilate malonate but not benzoate, and the inability to grow at 37°C could distinguish the two strains from all known Acinetobacter species. The two strains were subjected to whole genome sequencing using both short-read Illumina HiSeq2500 platform and the longread MinION sequencer. The average nucleotide identity and in silico DNA-DNA hybridization value between the genomes of WCHAc010005 and WCHAc010052 was 96.69% and 74.3% respectively, whereas those between the two genomes and the known Acinetobacter species were < 8...Continue Reading

References

Aug 3, 2006·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·L Poirel, P Nordmann
Jul 25, 2007·Antimicrobial Agents and Chemotherapy·Federico PerezRobert A Bonomo
Jan 8, 2009·International Journal of Systematic and Evolutionary Microbiology·Alexandr NemecLenie Dijkshoorn
Oct 27, 2009·Proceedings of the National Academy of Sciences of the United States of America·Michael Richter, Ramon Rosselló-Móra
Sep 30, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·J M RolainG Cornaglia
Apr 20, 2011·Microbes and Environments·Hamuel James DoughariSpinney Benade
Feb 26, 2013·BMC Bioinformatics·Jan P Meier-KolthoffMarkus Göker
Mar 10, 2015·Systematic and Applied Microbiology·Ramon Rosselló-Móra, Rudolf Amann
Aug 8, 2015·International Journal of Systematic and Evolutionary Microbiology·Lenka KrizovaAlexandr Nemec
Oct 4, 2016·International Journal of Systematic and Evolutionary Microbiology·Lenka Radolfova-KrizovaAlexandr Nemec
Jun 9, 2017·PLoS Computational Biology·Ryan R WickKathryn E Holt
Sep 13, 2017·International Journal of Systematic and Evolutionary Microbiology·Dong HuZongze Shao
Aug 18, 2018·International Journal of Systematic and Evolutionary Microbiology·Yiyi HuZhiyong Zong

❮ Previous
Next ❯

Citations

Sep 4, 2019·International Journal of Systematic and Evolutionary Microbiology·Aharon Oren, George Garrity
Apr 26, 2021·Journal of Global Antimicrobial Resistance·Zineb CherakJean-Marc Rolain
Aug 20, 2021·Current Microbiology·Rajeev Ranjan, Shashidhar Thatikonda

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Related Papers

International Journal of Systematic and Evolutionary Microbiology
Yiyi HuZhiyong Zong
International Journal of Systematic and Evolutionary Microbiology
Jiayuan QinZhiyong Zong
International Journal of Systematic and Evolutionary Microbiology
Lenka Radolfová-KřížováAlexandr Nemec
International Journal of Systematic and Evolutionary Microbiology
Lenka Radolfová-KřížováAlexandr Nemec
© 2022 Meta ULC. All rights reserved