Abstract
Acneiform dermatoses are follicular eruptions. The initial lesion is inflammatory, usually a papule or pustule. Comedones are later secondary lesions, a sequel to encapsulation and healing of the primary abscess. The earliest histological event is spongiosis, followed by a break in the follicular epithelium. The spilled follicular contents provokes a nonspecific lymphocytic and neutrophilic infiltrate. Acneiform eruptions are almost always drug induced. Important clues are sudden onset within days, widespread involvement, unusual locations (forearm, buttocks), occurrence beyond acne age, monomorphous lesions, sometimes signs of systemic drug toxicity with fever and malaise, clearing of inflammatory lesions after the drug is stopped, sometimes leaving secondary comedones. Other cutaneous eruptions that may superficially resemble acne vulgaris but that are not thought to be related to it etiologically are due to infection (e.g. gram-negative folliculitis) or unknown causes (e.g. acne necrotica or acne aestivalis).
Citations
Nov 24, 2004·American Journal of Clinical Dermatology·Jesús Luelmo-Aguilar, Mireia Sàbat Santandreu
Apr 29, 2003·Paediatric Drugs·Victoria Goulden
Mar 29, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M AaproA Ravaud
Dec 10, 2013·Clinics in Dermatology·Clio DessiniotiAndreas Katsambas
Feb 12, 2013·Journal of the American Academy of Dermatology·Tatyana A PetukhovaMeg R Gerstenblith
Apr 14, 2007·Dermatologic Clinics·Shari B ClarkeDiane M Thiboutot
Jul 24, 2004·The British Journal of Dermatology·W JacotB Guillot
Oct 27, 2011·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Helmut SchöferUNKNOWN Paul Ehrlich Society for Chemotherapy (PEG)
Mar 16, 2011·International Journal of Cosmetic Science·M Kanlayavattanakul, N Lourith
Oct 23, 2013·The Breast : Official Journal of the European Society of Mastology·Romualdo Barroso-SousaMax S Mano
Mar 10, 2017·Clinics in Dermatology·Jana Kazandjieva, Nikolay Tsankov
May 19, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·Florence PoliBrigitte Dréno
Apr 1, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M AaproA Ravaud