Acoustic analysis of voice in individuals with amyotrophic lateral sclerosis and perceptually normal vocal quality
Abstract
Currently, early phonatory changes in amyotrophic lateral sclerosis (ALS) are not well understood. The aim of this study was to compare acoustic parameters of voice in ALS subjects who demonstrated perceptually normal vocal quality on sustained phonation with a control group. We hypothesized that objective analysis of voice would reveal significant differences on specific acoustic parameters of voice compared to the control group. Results revealed statistically significant differences between the two groups on measures related to frequency range and phonatory stability. The findings suggest that early bulbar signs affecting the laryngeal system may be present in patients with ALS before the occurrence of perceptually aberrant vocal characteristics.
References
Citations
Quantitative voice analysis in the assessment of bulbar involvement in amyotrophic lateral sclerosis
Related Concepts
Related Feeds
Amyloid Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS) is a progressive nervous system disease associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.