Acquired inhibitor of factor V: first report in China and literature review

Haemophilia : the Official Journal of the World Federation of Hemophilia
L LuR Yang

Abstract

We reported a 51-year-old man who developed a severe haematuria with a prolonged prothrombin time (PT) and activated partial thromboplastin time (aPTT). Laboratory evaluation revealed the presence of specific factor V inhibitors. No underlying diseases and associated conditions have been identified. The patient improved after immunosuppressive therapy. However, the FV level remained low, indicating incomplete inhibitor eradication. The clinical course of our patient was consistent with the observations by others that FV inhibitor can be persistent for months or years.

References

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Citations

Nov 6, 2010·Journal of Thrombosis and Thrombolysis·Massimo Franchini, Giuseppe Lippi
Sep 21, 2005·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Ljiljana TukićSlavka Mandić-Radić
Dec 3, 2005·Hematology·Massimo Franchini, Dino Veneri
Jan 20, 2011·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Giuseppe LippiMassimo Franchini
May 15, 2009·British Journal of Haematology·Connie DuckersElisabetta Castoldi
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Jan 7, 2010·American Journal of Hematology·Anne Tessier-MarteauLaurent Macchi
Sep 27, 2006·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Viroj Wiwanitkit

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