Acquired left ventricle-to-right atrium shunt: clinical implications and diagnostic dilemmas

Wiener klinische Wochenschrift
Shi-Min Yuan

Abstract

The acquired left ventricle-to-right atrium (LV-RA) shunt (Gerbode defect) is rare but it can sometimes be a critical condition. The diagnosis is quite challenging largely due to its exotic anatomic features and diagnostic difficulties. This study aims to present the clinical features and diagnostic solutions of this rare lesion. Data source was based on a comprehensive literature retrieval of acquired LV-RA shunts of 1990-2014. Most of the acquired LV-RA shunts are of either a postoperative or an infective etiology. Transthoracic echocardiography showed a 62.2% accurate diagnosis, 13.4% inclusive diagnosis, 9.8% missed diagnosis, and 14.5% misdiagnosis rate. The accurate diagnostic rate of transthoracic echocardiography was significantly lower than that of the transesophageal echocardiography or cardiac catheterization. The LV-RA shunts are often misinterpreted as mitral regurgitation, pulmonary hypertension, tricuspid regurgitation, Valsalva aneurysm rupture, and subaortic/high perimembrane/residual ventricular septal defect. Surgical, interventional, and conservative treatments were applied in 57.8, 24.4, and 17.8% patients, respectively. Prognosis showed an event-free survival of 85%, a comorbidity of 9.1%, and a mortality ...Continue Reading

References

Jan 1, 1991·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·M BattinJ L Monro
Mar 1, 1991·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·W K Shen, B K Khandheria
May 1, 1967·The American Journal of Cardiology·T A Riemenschneider, A J Moss
Jul 1, 1995·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·T M WinslowM J Barry
May 1, 1995·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·T Dzwonczyk, W R Davidson
Jan 1, 1995·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·D ElianZ Vered
Jul 1, 1994·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·S KattaP K Mohanty
Jan 1, 1994·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·F S JoyceR G Trohman
Sep 1, 1996·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·J N NewmanT Kreulen
Jul 1, 1997·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Y JobicJ Boschat
Feb 24, 2001·The Annals of Thoracic Surgery·M WeinrichH J Schäfers
Mar 9, 2002·Echocardiography·Scott M WassermanBahaa M Fadel
May 20, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·N AlphonsoF Shabbo
Jul 22, 2006·International Journal of Cardiology·Yogesh RajaR W J Millner
Nov 7, 2006·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Vijay TrehanNaresh K Goyal
Oct 12, 2007·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Ali Reza MoarefMohammed Bagher Sharifkazemi
Nov 29, 2007·Interactive Cardiovascular and Thoracic Surgery·Christoph FriggRomano Mauri
Jun 27, 2008·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Shigeaki AoyagiHidetsugu Hori
Feb 10, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Kibar YaredRobert A Levine
Apr 23, 2009·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Réza DadkhahFabienne Lienart
Apr 28, 2009·Journal of Cardiovascular Computed Tomography·Dorinna D MendozaAllen J Taylor
Jun 9, 2009·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Peter MattFriedrich Eckstein
Jul 9, 2009·Journal of Cardiac Surgery·Ahmad Ali Amirghofran, Abbas Emaminia
Jan 26, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Daniela LaxVincent L Sorrell
Jan 28, 2010·The Annals of Thoracic Surgery·Peter MattFriedrich Eckstein
May 4, 2010·Journal of Cardiothoracic and Vascular Anesthesia·Priya A KumarGosta Petterson
Jun 29, 2010·Journal of the American College of Cardiology·Amit K PursnaniItzhak Kronzon
Oct 6, 2010·Cardiovascular Ultrasound·Nereida XhabijaFatmir Sula
Mar 24, 2011·Echocardiography·Prashanth Panduranga, Mohammed Mukhaini
Apr 26, 2011·Heart, Lung & Circulation·Vivek PillaiJayakumar Karunakaran
May 31, 2011·The Journal of Emergency Medicine·Nicolas PortetOlivier Fourcade
Jun 9, 2011·Journal of Cardiovascular Electrophysiology·Ajay K SharmaJagmeet P Singh
Sep 24, 2011·AJR. American Journal of Roentgenology·Prabhakar Rajiah, Jeffrey P Kanne

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