Specialization of function in the left hemisphere of man, as compared with the right, was studied with special reference to the nature of the impairments seen after left-hemisphere damage. Patients with unilateral lesions of the left or the right hemisphere were compared in the acquisition and subsequent performance of a manual skill requiring several hand movements. Patients with left-hemisphere damage were further subdivided into aphasic and non-aphasic groups. Patients with left-hemisphere damage were further subdivided into aphasic and non-aphasic groups. Patients with left-hemisphere damage, whether aphasic or not, were impaired in the acquisition of the task, relative to patients with right hemisphere damage, although aphasics were most severely impaired. Analysis of the errors made during acquisition indicated that perseverative errors and unique errors (unrelated movements) differentiated the left and right groups, but that sequencing errors did not. It was concluded that a major function of the left hemisphere is the control of changes in limb or articulatory posture, and that its complex verbal and praxic functions are derived from such control.
The role of the left hemisphere in motor control of touch: a functional magnetic resonance imaging analysis
Motor representation of the hand in the human cortex: an f-MRI study with a conventional 1.5 T clinical unit
Laterality affects spontaneous recovery of contralateral hand motor function following motor cortex injury in rhesus monkeys
Competition within the left hemisphere between speaking and unimanual tasks performed without visual guidance
Interference between concurrent speaking and sequential finger tapping: both hands show a performance decrement under both visual and non-visual guidance
Hemispheric asymmetries in motor function: II. Ordering does not contribute to left-hemisphere specialization
Sequence ability in parkinsonians, patients with frontal lobe lesions and patients who have undergone unilateral temporal lobectomies
Constraints on grip selection in hemiparetic cerebral palsy: effects of lesional side, end-point accuracy, and context
Hemispheric specialisation for imitation of hand-head positions and finger configurations: a controlled study in patients with complete callosotomy
Hemispheric asymmetry of ipsilateral motor cortex activation during unimanual motor tasks: further evidence for motor dominance
Cerebral specialization and the control of oral and limb movements for individuals with Down's syndrome
Dissociable distal and proximal motor components: Evidence from perseverative errors in three apraxic patients
Action errors and dressing disability after stroke: an ecological approach to neuropsychological assessment and intervention
Disturbances in everyday life activities and sequence disabilities in tool use for Alzheimer disease and vascular dementia
Probing for hemispheric specialization for motor skill learning: a transcranial direct current stimulation study
Lateral difference in the reproduction of arm positioning movement: an examination of the hypothesis on the levels of psychological processes
Apraxia in mild cognitive impairment and Alzheimer's disease: validity and reliability of the Van Heugten test for apraxia
Spatial field advantages for tactile line bisection as a function of hemispheric specialisation inferred from dichotic listening
Hemispheric asymmetries in motor function: I. Left-hemisphere specialization for memory but not performance
Measurement of integrated sensory-motor function following brain damage by a computerized preview tracking task
No transfer of visuomotor learning of button-pressing from right to left hands in right-handed four-year-olds
Bugs and faces in the two visual fields: the analytic/holistic processing dichotomy and task sequencing
Performance of left brain-damaged patients on imitation of single movements and motor sequences. Frontal and parietal-injured patients compared
Isolated and sequenced oral motor posture production under different input modalities by left-hemisphere damaged adults
A novel technique for the quantitative assessment of apraxic deficits: application to individuals with mild cognitive impairment
Cerebral control for speech in right-handers and left-handers: an analysis of the views of Paul Broca, his contemporaries, and his successors
Suppression of the non-dominant motor cortex during bimanual symmetric finger movement: a functional magnetic resonance imaging study
Changes in the execution of a complex manual task after ipsilateral ischemic cerebral hemispheric stroke
Neural correlates of motor impairment during motor imagery and motor execution in sub-cortical stroke
Cerebral organization of motor programming and verbal processing as a function of degree of hand preference and familial sinistrality
Impaired imitation of meaningless gestures in ideomotor apraxia: a conceptual problem not a disorder of action control? A single case investigation
Brain oxygenation patterns during the execution of tool use demonstration, tool use pantomime, and body-part-as-object tool use
Hemispheric specialization in the co-ordination of arm and trunk movements during pointing in patients with unilateral brain damage
The right cerebral hemisphere: emotion, music, visual-spatial skills, body-image, dreams, and awareness
Head and body hemispace to left and right III: Vibrotactile stimulation and sensory and motor components
Maximal grip force in chronic stroke subjects and its relationship to global upper extremity function
The neuropsychology of development hemispheric laterality, limbic language, and the origin of thought
Handedness results from complementary hemispheric dominance, not global hemispheric dominance: evidence from mechanically coupled bilateral movements.
Asymmetric activation of motor cortex controlling human anterior digastric muscles during speech and target-directed jaw movements
Processing of symbolic and nonsymbolic events: a review of comparisons in selected cognitive activities
Noninvasive tongue stimulation combined with intensive cognitive and physical rehabilitation induces neuroplastic changes in patients with multiple sclerosis: A multimodal neuroimaging study
Manual asymmetries: feedback processing, output variability, and spatial complexity-resolving some inconsistencies
Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.
Alzheimer's Disease: MS4A
Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.
Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.
Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.
Genetic Screens in iPSC-derived Brain Cells
Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.
This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.
Chronic Fatigue Syndrome
Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.
Pharmacology of Proteinopathies
This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.
Alignment-free Sequence Analysis Tools
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