Acquisition of anal human papillomavirus (HPV) infection in women: the Hawaii HPV Cohort study

The Journal of Infectious Diseases
Marc T GoodmanBrenda Y Hernandez

Abstract

The majority of anal cancer is associated with human papillomavirus (HPV) infection, yet little is known about women's risk of acquisition of anal HPV infection. Risk factors for the acquisition of anal HPV infection were examined in a longitudinal cohort study of 431 women, via repeated measurement of HPV DNA. Seventy percent of women were positive for anal HPV infection at one or more clinic visits from baseline through a follow-up period that averaged 1.3 years. The incidence of a high-risk (HR) infection was 19.5 (95% confidence interval [CI], 16.0-23.6) per 1000 woman-months. The most common incident HR HPV types were HPV-53, -52 and -16. The presence of an HR anal HPV infection at baseline increased the risk of an incident anal infection by 65%. Baseline HR cervical HPV infection also predicted the acquisition of an HR anal HPV infection (odds ratio, 1.81 [95% CI, 1.09-3.02]). Nonviral risk factors for acquisition of HR HPV infection included younger age, lower socioeconomic status, greater lifetime number of sexual partners, past use of hormones, and condom use. The results of this study suggest that women's risk of anal HPV infection is as common as their risk of cervical HPV infection.

References

Jan 15, 1992·American Journal of Epidemiology·J R DalingN S Weiss
Jul 1, 1992·American Journal of Epidemiology·C S RabkinR E Curtis
Mar 1, 1991·Statistics in Medicine·A J DobsonJ Scherer
Jul 1, 1988·Gastroenterology·F HolmesG Holmes
Jul 1, 1994·American Journal of Epidemiology·M FrischM Melbye
Feb 13, 1993·BMJ : British Medical Journal·M FrischH Møller
Nov 14, 1997·The New England Journal of Medicine·M FrischM Melbye
Apr 21, 1999·International Journal of Cancer. Journal International Du Cancer·N YlitaloH O Adami
Aug 12, 1999·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·M J Hill
Jan 5, 2000·Journal of Clinical Microbiology·P E GravittR J Apple
Mar 16, 2000·The New England Journal of Medicine·D P RyanR J Mayer
Sep 9, 2000·The Journal of Infectious Diseases·K K ThomasL A Koutsky
Nov 20, 2002·Sexually Transmitted Diseases·Lisa E Manhart, Laura A Koutsky
Apr 11, 2003·Lancet·Jennifer S SmithValerie Beral
Jun 9, 2004·Virology·Ethel-Michele de VilliersHarald zur Hausen
Nov 11, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Elizabeth Y ChiaoDeborah Schrag
Nov 15, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Brenda Y HernandezMarc T Goodman
Jan 13, 2006·Vaccine·Helen Trottier, Eduardo L Franco
May 25, 2006·British Journal of Cancer·D H Brewster, L A Bhatti
Sep 5, 2006·Vaccine·Nubia MuñozLutz Gissmann
Sep 5, 2006·Vaccine·D Maxwell Parkin, Freddie Bray
Nov 23, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Salvatore VaccarellaSilvia Franceschi

❮ Previous
Next ❯

Citations

Oct 28, 2011·The New England Journal of Medicine·Joel M PalefskyElizabeth I O Garner
Sep 8, 2012·Sexual Health·François CoutléeEduardo L Franco
Sep 11, 2012·Sexual Health·Andrew E GrulichRichard J Hillman
Feb 6, 2013·Sexual Health·Andrew E GrulichChristopher K Fairley
Feb 5, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Yurii B ShvetsovMarc T Goodman
Mar 24, 2010·The Journal of Infectious Diseases·Marc T GoodmanBrenda Y Hernandez
Oct 9, 2012·Journal of the National Cancer Institute·Meredith S ShielsEric A Engels
May 6, 2011·Journal of Lower Genital Tract Disease·Anna-Barbara Moscicki, Joel M Palefsky
Jun 19, 2013·Journal of Lower Genital Tract Disease·Daron FerrisFiyinfoluwa Fawole
Aug 11, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Anna-Barbara MoscickiStephen Shiboski
Sep 11, 2012·BMC Cancer·Margaret A StanleyPeter K C Goon
Dec 7, 2011·Journal of Health Care for the Poor and Underserved·Ahoora PayamDominic Chow
Jun 18, 2014·International Journal of Colorectal Disease·Reto KaderliLukas E Brügger
Dec 5, 2012·Vaccine·Anna-Barbara MoscickiJoel Palefsky
Jun 9, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Kathleen W M D'HauwersWiebren A A Tjalma
May 23, 2012·The Journal of Infection·Alessandra PierangeliMarileda Indinnimeo
Mar 30, 2010·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Joel M Palefsky
Jan 1, 2008·Journal of Infection and Public Health·Kamalesh SarkarBaishali Bal
Mar 11, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alan G NyitrayAnna R Giuliano
Jun 6, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Shamita B ShahMark Welton
Mar 24, 2015·American Journal of Obstetrics and Gynecology·Elizabeth A StierElizabeth Y Chiao
Jun 2, 2012·Asia-Pacific Journal of Public Health·Brenda Y HernandezVictor Tofaeono Williams
Feb 27, 2018·Journal of Lower Genital Tract Disease·Amy J BregarKatina Robison
May 29, 2014·Expert Review of Anti-infective Therapy·Sebastián VidelaGuillem Sirera
Jul 15, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Alyssa LarishKathryn Van Abel
Jun 24, 2015·Journal of Lower Genital Tract Disease·Anna-Barbara MoscickiJoel M Palefsky
Apr 7, 2016·Expert Review of Anti-infective Therapy·Maria BenevoloSusanna Chiocca
Oct 18, 2016·Journal of Clinical Gastroenterology·Michele Limoges-Gonzalez, Amar Al-Juburi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Yurii B ShvetsovMarc T Goodman
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Brenda Y HernandezMarc T Goodman
© 2022 Meta ULC. All rights reserved