Abstract
Patients with locally advanced invasive breast cancers are often treated with neoadjuvant chemotherapy prior to definitive surgical intervention. The primary aims of this approach are to: 1) reduce tumor burden thereby permitting breast conservation rather than mastectomy; 2) promptly treat possible metastatic disease, whether or not it is detectable on preoperative staging; and 3) potentially tailor future chemotherapeutic decisions by monitoring in-vivo tumor response. Accurate radiological assessment permits optimal management and planning in this population. However, assessment of tumor size and response to treatment can vary depending on the modality used, the measurement technique (such as single longest diameter, 3-D measurements, or calculated tumor volume), and varied response of different tumor subtypes to neoadjuvant chemotherapy (such as concentric shrinkage or tumor fragmentation). As discussed in further detail, digital mammography, digital breast tomosynthesis, US and MRI represent the key modalities with potential to help guide patient management. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidiscipli...Continue Reading
Citations
Mar 6, 2019·AJR. American Journal of Roentgenology·Linda M SandersAvani Mehta
Aug 14, 2019·Radiology·Rihyeon KimWoo Kyung Moon
Apr 22, 2020·Radiology·Jung Min ChangWoo Kyung Moon
Jul 29, 2019·BMC Surgery·Chih-Yu KuoShih-Hsin Tu
Aug 16, 2019·Radiology·Gary J Whitman
Jul 7, 2020·Tumori·Eduardo ReyesOctavi Cordoba
Jan 29, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Larissa A KordeDawn L Hershman
Jan 17, 2021·Clinical Breast Cancer·Xiaomei HuangZaiyi Liu
Nov 7, 2020·CA: a Cancer Journal for Clinicians·David R ByrdDonna M Gress
Jun 14, 2021·Breast Cancer Research and Treatment·Ida SkarpingLisa Rydén
Aug 5, 2021·Japanese Journal of Clinical Oncology·Jie FeiJing Jing Chen
Aug 13, 2021·Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes·Anabel M Scaranelo
Aug 17, 2021·Radiologic Clinics of North America·Amy M Fowler, Steve Y Cho
Oct 17, 2020·Acta Oncologica·Ida SkarpingSigne Borgquist
Sep 2, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Hannah L ChungJessica W T Leung
May 28, 2021·Chinese Medical Journal·Chao ZhengUNKNOWN Chinese Society of Breast Surgery
Oct 16, 2021·European Radiology·I SkarpingD Förnvik
Jan 12, 2022·European Radiology·Nathalie A HottatMieke M Cannie