Acridone Alkaloids from Swinglea glutinosa (Rutaceae) and Their Effects on Photosynthesis

Chemistry & Biodiversity
Pedro H Arato FerreiraThiago A M Veiga

Abstract

Continuing our search for herbicide models based on natural products, we investigated the action mechanisms of five alkaloids isolated from Swinglea glutinosa (Rutaceae): Citrusinine-I (1), glycocitrine-IV (2), 1,3,5-trihydroxy-10-methyl- 2,8-bis(3-methylbut-2-en-1-yl)-9(10H)-acridinone (3), (2R)-2-tert-butyl-3,10-dihydro-4,9-dihydroxy-11-methoxy-10-methylfuro[3,2-b]acridin-5(2H)-one (4), and (3R)-2,3,4,7-tetrahydro-3,5,8-trihydroxy-6-methoxy-2,2,7-trimethyl-12H-pyrano[2,3-a]acridin-12-one (5) on several photosynthetic activities in an attempt to find new compounds that affect photosynthesis. Through polarographic techniques, the compounds inhibited the non-cyclic electron transport in the basal, phosphorylating, and uncoupled conditions from H2 O to methylviologen (=MV). Therefore, they act as Hill reaction inhibitors. This approach still suggested that the compounds 4 and 5 had their interaction site located at photosystem I. Studies on fluorescence of chlorophyll a suggested that acridones (1-3) have different modes of interaction and inhibition sites on the photosystem II electron transport chain.

References

May 1, 1979·Antimicrobial Agents and Chemotherapy·J G AllenP S Ringrose
Jan 1, 1972·Methods in Enzymology·R A Dilley
Jan 18, 1973·Biochimica Et Biophysica Acta·R H Vallejos
Jan 18, 1974·Biochimica Et Biophysica Acta·R H Vallejos, C S Andreo
Sep 30, 2010·Journal of Agricultural and Food Chemistry·David Torres-RomeroIsabel L Bazzocchi
Feb 1, 2011·Bioorganic & Medicinal Chemistry·Richele P SeverinoPaulo C Vieira
Mar 2, 2011·American Journal of Veterinary Research·G Robert ColborneLisa S Kirk
Dec 3, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Djalma Menezes-de-OliveiraBlas Lotina-Hennsen
Jan 11, 2012·Pest Management Science·Franck E DayanStephen O Duke
Feb 19, 2013·Journal of Photochemistry and Photobiology. B, Biology·Thiago André Moura VeigaBlas Lotina-Hennsen
May 3, 2014·Plant Physiology·Franck E Dayan, Stephen O Duke
Jun 10, 2014·Journal of Photochemistry and Photobiology. B, Biology·Martha Lydia Macías-RubalcavaBlas Lotina-Hennsen
Nov 19, 2014·Journal of Agricultural and Food Chemistry·James N SeiberAaron D Gross

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Citations

Nov 16, 2018·MedChemComm·Parteek Prasher, Mousmee Sharma
Jan 8, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ana Calheiros de CarvalhoThiago André Moura Veiga
Sep 23, 2020·Chemistry & Biodiversity·Vanessa Gisele Pasqualotto SeverinoThiago André Moura Veiga
Dec 2, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Burtram C FieldingDamião Pergentino de Sousa

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