PMID: 6167334Aug 31, 1981Paper

Acrylamide and 2,5-hexanedione neuropathies: abnormal bidirectional transport rate in distal axons

Brain Research
Z Sahenk, J R Mendell

Abstract

Events taking place in the distal axon including delivery, turn-around and return of labelled materials toward the cell body were examined in 2,5-hexanedione (2,5-HD) and acrylamide-induced neuropathies. Retrograde transport profiles obtained from 2,5-HD as well as acrylamide intoxicated axons demonstrated a delay in the time of onset of accumulation and a decrease in the amount of returning activity to the distal collection segment. Integral analysis of the data indicated a decrease in bidirectional transport rate within the distal axons rather than a failure in the turn-around process at the nerve terminal.

Citations

Mar 1, 1992·Journal of Neuroscience Research·G J HarryT W Bouldin
Mar 27, 1989·Brain Research·M I SabriP S Spencer
Aug 1, 1985·Experimental Neurology·A B Sterman, M R Delannoy
Dec 1, 1986·Journal of the Neurological Sciences·L B DahlinW G McLean
Aug 1, 1985·Toxicology Letters·D W Sickles, B D Goldstein
Sep 13, 2002·Neurotoxicology·Dale W SicklesMarvin A Friedman
Aug 20, 1992·The New England Journal of Medicine·K W Williams
Aug 1, 1993·Journal of Toxicology and Environmental Health·S PadillaA C Breuer
Sep 1, 1986·Journal of Neurology, Neurosurgery, and Psychiatry·J JakobsenH Braendgaard
Jan 1, 1984·Journal of Toxicology and Environmental Health·R J Anderson, C B Dunham
Jun 1, 1990·Neurochemical Research·M I Sabri, P S Spencer
Jan 1, 1985·Mayo Clinic Proceedings·W S Brimijoin, P I Hammond
May 1, 1990·Toxicology and Applied Pharmacology·L N Berti-MatteraR M LoPachin
May 1, 1984·Neuropathology and Applied Neurobiology·A B Sterman
Nov 1, 1984·Journal of Neurochemistry·M S Miller, P S Spencer
Jan 1, 1984·Journal of Neuroscience Research·E P LapinG M Lehrer
Jun 1, 1994·Developmental Medicine and Child Neurology·C L Crawford, M J Hobbs
Oct 1, 1986·Journal of Neurochemistry·D J FinkM Mata
Jan 1, 1988·Annals of Neurology·J W Griffin, D F Watson
Feb 1, 1983·Muscle & Nerve·J JakobsenP Sidenius
Jan 1, 1987·Muscle & Nerve·Z SahenkJ R Mendell

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