Actigraph measures discriminate pediatric bipolar disorder from attention-deficit/hyperactivity disorder and typically developing controls

Journal of Child Psychology and Psychiatry, and Allied Disciplines
Gianni L FaeddaMartin H Teicher

Abstract

Distinguishing pediatric bipolar disorder (BD) from attention-deficit hyperactivity disorder (ADHD) can be challenging. Hyperactivity is a core feature of both disorders, but severely disturbed sleep and circadian dysregulation are more characteristic of BD, at least in adults. We tested the hypothesis that objective measures of activity, sleep, and circadian rhythms would help differentiate pediatric subjects with BD from ADHD and typically developing controls. Unmedicated youths (N = 155, 97 males, age 5-18) were diagnosed using DSM-IV criteria with Kiddie-SADS PL/E. BD youths (n = 48) were compared to typically developing controls (n = 42) and children with ADHD (n = 44) or ADHD plus comorbid depressive disorders (n = 21). Three-to-five days of minute-to-minute belt-worn actigraph data (Ambulatory Monitoring Inc.), collected during the school week, were processed to yield 28 metrics per subject, and assessed for group differences with analysis of covariance. Cross-validated machine learning algorithms were used to determine the predictive accuracy of a four-parameter model, with measures reflecting sleep, hyperactivity, and circadian dysregulation, plus Indic's bipolar vulnerability index (VI). There were prominent group dif...Continue Reading

References

Jul 1, 1990·Statistics in Medicine·Y Hochberg, Y Benjamini
Jun 1, 1990·Computers and Biomedical Research, an International Journal·M H Teicher, N I Barber
Jun 1, 1974·Archives of General Psychiatry·D J KupferR McPartland
Jul 1, 1993·Journal of the American Academy of Child and Adolescent Psychiatry·M H TeicherK Pahlavan
Jan 1, 1995·Transactions of the American Ophthalmological Society·J F KoretzP L Kaufman
Oct 1, 1996·Journal of the American Academy of Child and Adolescent Psychiatry·C A Glod, M H Teicher
Feb 1, 1997·Journal of the American Academy of Child and Adolescent Psychiatry·C A GlodY Ito
Feb 1, 1997·Archives of General Psychiatry·M H TeicherC E McGreenery
May 1, 1995·Harvard Review of Psychiatry·M H Teicher
Nov 1, 1995·Harvard Review of Psychiatry·G L FaeddaD S Lipschitz
Mar 10, 2001·Physiology & Behavior·G Jean-LouisR D Langer
Jul 1, 2004·Bipolar Disorders·Gianni L FaeddaNancy B Austin
Aug 4, 2005·Chronobiology International·Kristiaan B Van der HeijdenW Boudewijn Gunning
Feb 24, 2006·Sleep·Rochelle C MehlDavid Gozal
Jan 24, 2007·Journal of the American Academy of Child and Adolescent Psychiatry·Kristiaan B Van der HeijdenW Boudewijn Gunning
Mar 21, 2007·Journal of Family Psychology : JFP : Journal of the Division of Family Psychology of the American Psychological Association (Division 43)·Nicholas LofthouseKelly Kelleher
Apr 25, 2007·The Journal of Pediatrics·Gabriele S LeverichDavid Luckenbaugh
May 9, 2007·Archives of General Psychiatry·Kathleen R MerikangasRonald C Kessler
Jan 15, 2008·Journal of Pediatric Psychology·Nicholas LofthouseSusan Resko
Feb 15, 2008·Bipolar Disorders·Paola SalvatoreRoss J Baldessarini
Apr 9, 2008·Archives of Pediatrics & Adolescent Medicine·Allan HvolbyNiels Bilenberg
Jul 25, 2009·Journal of the American Academy of Child and Adolescent Psychiatry·Samuele CorteseMichel Lecendreux
Jun 16, 2011·The Journal of Clinical Psychiatry·Anna R Van MeterEric A Youngstrom
Oct 4, 2011·Journal of the American Academy of Child and Adolescent Psychiatry·David A AxelsonMartin B Keller
Mar 29, 2012·Frontiers in Psychiatry·Argelinda BaroniGianni L Faedda
Oct 27, 2012·Neuroscience and Biobehavioral Reviews·Martijn Arns, J Leon Kenemans
Jun 15, 2015·Seminars in Pediatric Neurology·Kanwaljit Singh, Andrew W Zimmerman

❮ Previous
Next ❯

Citations

Jun 28, 2016·Journal of the American Academy of Child and Adolescent Psychiatry·Anna R Van MeterChristoph U Correll
Aug 16, 2016·Sleep Medicine Reviews·Matias C A MeloVeralice M S de Bruin
Apr 20, 2018·Physiological Measurement·Erik Reinertsen, Gari D Clifford
Sep 28, 2018·Personalized Medicine·Jessilyn DunnMichael Snyder
Jun 25, 2017·BMJ Open·Lars Vedel KessingMaj Vinberg
Feb 13, 2019·Psychological Medicine·Adrian B R ShatteSamantha J Teague
Aug 23, 2019·Translational Psychiatry·Niall M McGowanKate E A Saunders
Jan 9, 2017·Attention Deficit and Hyperactivity Disorders·Andrew N Coogan, Niall M McGowan
Mar 23, 2017·Current Psychiatry Reports·Lauren B AlloyElaine M Boland
Apr 9, 2020·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Giselli ScainiJoao Quevedo
Jun 25, 2020·Stroke; a Journal of Cerebral Circulation·Ho-Yan Yvonne ChunWilliam N Whiteley
Aug 26, 2019·Journal of the American Academy of Child and Adolescent Psychiatry·Lydia SequeiraJohn Strauss
Oct 11, 2020·Journal of the American Academy of Child and Adolescent Psychiatry·Anna R Van MeterRobert L Findling
Dec 14, 2019·Current Opinion in Biomedical Engineering·Daniel WittJessilyn Dunn
Apr 3, 2021·International Journal of Bipolar Disorders·Scott MonteithMichael Bauer
Aug 15, 2021·International Journal of Methods in Psychiatric Research·Reut NaimMelissa A Brotman
Dec 22, 2021·PloS One·Bálint MaczákZoltán Gingl

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

© 2022 Meta ULC. All rights reserved