Actin dynamics associated with focal adhesions.

International Journal of Cell Biology
Corina CiobanasuChristophe Le Clainche

Abstract

Cell-matrix adhesion plays a major role during cell migration. Proteins from adhesion structures connect the extracellular matrix to the actin cytoskeleton, allowing the growing actin network to push the plasma membrane and the contractile cables (stress fibers) to pull the cell body. Force transmission to the extracellular matrix depends on several parameters including the regulation of actin dynamics in adhesion structures, the contractility of stress fibers, and the mechanosensitive response of adhesion structures. Here we highlight recent findings on the molecular mechanisms by which actin assembly is regulated in adhesion structures and the molecular basis of the mechanosensitivity of focal adhesions.

References

Aug 1, 1990·The Journal of Cell Biology·C A OteyK Burridge
Jan 1, 1986·The Journal of Cell Biology·G LangangerJ De Mey
Nov 1, 1993·The Journal of Cell Biology·A B Verkhovsky, G G Borisy
Jun 1, 1996·The Journal of Cell Biology·M Chrzanowska-Wodnicka, K Burridge
Sep 18, 1998·Biochimica Et Biophysica Acta·J V SmallK I Anderson
Mar 24, 1999·The Journal of Cell Biology·V LaurentM F Carlier
Nov 2, 1999·The EMBO Journal·R Bourdet-SicardG T Nhieu
Nov 13, 1999·Nature Cell Biology·N WatanabeS Narumiya
Nov 13, 1999·Nature Cell Biology·K RottnerJ Wehland
Dec 30, 1999·The Journal of Cell Biology·B E DreesM C Beckerle
Aug 3, 2001·Nature Cell Biology·J FradeliziE Friederich
Aug 30, 2001·Current Biology : CB·L BlanchoinS E Hitchcock-DeGregori
Oct 13, 2001·The EMBO Journal·F CastellanoP Chavrier
Mar 20, 2002·The Journal of Cell Biology·Shoichiro Ono, Kanako Ono
Oct 4, 2003·Science·Seiji TadokoroDavid A Calderwood
Oct 15, 2003·The Journal of Cell Biology·Stanislav SamarinMarie-France Carlier
Oct 25, 2003·Journal of Cell Science·Ronen Zaidel-BarBenjamin Geiger
Dec 6, 2003·Science·Anne J RidleyAlan Rick Horwitz
Jan 2, 2004·Nature·Tina IzardPhilippe R J Bois
Feb 18, 2005·The Journal of Cell Biology·Stephanie L GuptonClare M Waterman-Storer
Mar 9, 2005·Trends in Cell Biology·Weigang WangJohn S Condeelis
Jan 28, 2006·Cell·David R KovarThomas D Pollard
Apr 6, 2006·European Journal of Cell Biology·Ruth M SaundersDavid R Critchley
May 3, 2006·The Journal of Cell Biology·Pirta Hotulainen, Pekka Lappalainen
May 6, 2006·Proceedings of the National Academy of Sciences of the United States of America·Antje SchirenbeckJan Faix
May 11, 2006·Journal of Structural Biology·David Chereau, Roberto Dominguez
Jan 6, 2007·Science·Ke HuClare M Waterman-Storer
Mar 22, 2007·Annual Review of Biochemistry·Bruce L Goode, Michael J Eck
Aug 4, 2007·Science·Colin P JohnsonDennis E Discher
Oct 12, 2007·Journal of Cell Science·Stéphanie Pellegrin, Harry Mellor
Apr 9, 2008·Physiological Reviews·Christophe Le Clainche, Marie-France Carlier
Aug 30, 2008·Journal of Microscopy·P NaumanenP Hotulainen
Jan 31, 2009·Science·Armando del RioMichael P Sheetz
Feb 7, 2009·Nature Reviews. Molecular Cell Biology·Benjamin GeigerAlexander D Bershadsky

❮ Previous
Next ❯

Citations

Dec 12, 2012·Cell and Tissue Research·Nickolay V BukoreshtlievAndrew E Pelling
Apr 5, 2014·Journal of Cellular Biochemistry·K P GoetschC U Niesler
May 23, 2015·PloS One·Benjamin EltznerFlorian Rehfeldt
Apr 7, 2015·Archives of Dermatological Research·Verena Natalie LorenzCornelia S Seitz
Dec 26, 2017·The Journal of Biological Chemistry·Corina CiobanasuChristophe Le Clainche
Mar 23, 2019·Journal of Developmental Biology·Charlotte A Kelley, Erin J Cram
Mar 17, 2020·Cellular Microbiology·Arturo Aguilar-RojasNancy Guillen
Oct 9, 2020·Development·Vassilis PapalazarouLaura M Machesky
Jan 24, 2021·Proceedings of the National Academy of Sciences of the United States of America·Christoph SchreiberMartin Falcke
Apr 1, 2020·Current Stem Cell Research & Therapy·Haiping LiuXiaodong Wang
May 20, 2021·American Journal of Physiology. Lung Cellular and Molecular Physiology·Debra T LinfieldFariba Rezaee

❮ Previous
Next ❯

Methods Mentioned

BETA
fluorescence microscopy
biosensor
magnetic tweezers

Software Mentioned

VASP

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.