Actinobacillus pleuropneumoniae Interaction With Swine Endothelial Cells

Frontiers in Veterinary Science
Berenice Plasencia-MuñozAlma L Guerrero-Barrera

Abstract

Actinobacillus pleuropneumonia is a swine (host) specific respiratory pathogen and the etiological agent of swine pleuropneumonia which affects pigs of all ages, many being asymptomatic carriers. This pathogen has high morbidity and mortality rates which generates large economic losses for the pig industry. Actinobacillus pleuropneumoniae is a widely studied bacterium, however its pathogenesis is not yet fully understood. The prevalence of the 18 serotypes of A. pleuropneumoniae varies by geographic region, in North American area, more specifically in Mexico, serotypes 1, 3, 5b, and 7 show higher prevalence. Actinobacillus pleuropneumoniae is described as a strict extracellular pathogen with tropism for lower respiratory tract. However, this study depicts the ability of these serotypes to adhere to non-phagocytic cells, using an endothelial cell model, as well as their ability to internalize them, proposing it could be considered as an intracellular pathogen.

References

Jan 1, 1991·Research in Veterinary Science·S SerebrinP B Little
Oct 1, 1996·Infection and Immunity·J L BurnsA Griffith
Jun 30, 2000·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·D J PhilpottP J Sansonetti
Mar 7, 2002·Microbes and Infection·Janine T BosséPaul R Langford
Jan 7, 2003·Methods in Molecular Biology·Joachim Frey
Aug 2, 2003·Journal of Cellular Physiology·Carine Michiels
Feb 24, 2004·Infection and Immunity·Ghyslaine VanierMarcelo Gottschalk
Jul 17, 2004·Microbiology·Idalia Enríquez-VerdugoMireya de la Garza
Nov 18, 2005·Genes & Development·Meta J Kuehn, Nicole C Kesty
Dec 31, 2005·Microbiology·Ghyslaine VanierMarcelo Gottschalk
Feb 25, 2006·Cell·Javier Pizarro-Cerdá, Pascale Cossart
Nov 28, 2007·Annual Review of Pathology·Gustavo Valbuena, David H Walker
Oct 3, 2008·In Vitro Cellular & Developmental Biology. Animal·J A Burciaga-NavaA L Guerrero-Barrera
Jan 23, 2009·Current Opinion in Microbiology·Emma J McGhieVassilis Koronakis
Aug 12, 2009·Veterinary Microbiology·S OjhaJ I MacInnes
Sep 15, 2009·The Veterinary Journal·Virginia AragonMarcelo Gottschalk
Nov 17, 2009·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Jane B TaylorCarolyn L Cannon
Dec 17, 2009·Methods in Molecular Biology·Maria Célia Jamur, Constance Oliver
Dec 31, 2009·Nature Reviews. Microbiology·Emmanuel LemichezSandrine Bourdoulous
Dec 15, 2010·The Journal of Pharmacology and Experimental Therapeutics·A L RisingerS L Mooberry
Jan 1, 1988·Methods in Molecular Biology·J B Hammond, N J Kruger
Mar 30, 2011·Journal of Visualized Experiments : JoVE·Andrew M Edwards, Ruth C Massey
Jun 3, 2011·Journal of Visualized Experiments : JoVE·Jason LetourneauMichael Mourez
Oct 15, 2013·BMC Veterinary Research·Rafael FrandolosoCésar B Gutiérrez Martín
Nov 20, 2013·International Journal of Biological Sciences·Peramaiyan RajendranIkuo Nishigaki
Jul 16, 2014·Current Opinion in Infectious Diseases·Anjana KalitaAlfredo G Torres
Dec 24, 2014·Nature Reviews. Microbiology·Jean Celli, Renée M Tsolis
Apr 9, 2015·PloS One·Seung-Il ChoiEung Kweon Kim
Jan 8, 2016·The Journal of Infectious Diseases·Jemiina SaloJukka Hytönen

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Citations

Feb 26, 2021·Microbiology and Immunology·Qunzhi WangHua Zhou

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