Actinomyces lymphadenitis

Proceedings
John KimHaala Rokadia

Abstract

Actinomyces is a gram-positive anaerobe that colonizes the human oral cavity. Its pathogenesis involves the disruption of the mucosal membrane, leading to suppuration and subsequent abscess formation, most commonly in the cervicofacial region. The bacteria form masses consisting of aggregates of branching, filamentous bacilli. They typically spread by direct tissue invasion and less commonly through hematogenous spread. Lymphatic spread is extremely uncommon. To the best of our knowledge, only two cases have been reported with lymph node involvement. Clinically, lymphadenopathy associated with Actinomyces may be misinterpreted as malignancy, causing unnecessary surgical interventions when only antibiotics are warranted. This case highlights the importance of properly diagnosing a rare phenomenon of Actinomyces lymphadenitis.

References

Oct 18, 2000·Archives of Pathology & Laboratory Medicine·M AmrikachiI Shahab
Oct 31, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Janine ReichenbachSteven M Holland
Jun 7, 2014·BMJ Case Reports·Diogo Ferreira BranquinhoCarlos Sofia
Jul 22, 2014·Infection and Drug Resistance·Florent ValourTristan Ferry
Mar 20, 2015·Clinical Microbiology Reviews·Eija Könönen, William G Wade
Sep 26, 2015·Journal of the Pediatric Infectious Diseases Society·Kathi WaltherNicole Ritz

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