PMID: 5890452Sep 24, 1965

Actinomycin D: inhibition of protein synthesis unrelated to effect on template RNA synthesis

Science
G R Honig, M Rabinovitz

Abstract

Incubation of sarcoma-37 ascites cells in vitro with actinomycin D resulted in inhibition of synthesis of nuclear and cytoplasmic proteins. The overall inhibition could be prevented or relieved by glucose; it is thus unrelated to breakdown of template RNA.

Citations

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Related Concepts

Carbon Isotopes
Ac-De
Glucose, (beta-D)-Isomer
Lysine Hydrochloride
Nuclear Track Detection
RNA, Neoplasm
Sarcoma 37
Protein Biosynthesis
Culture Techniques

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