May 1, 1977

Action of androgens and one anti-androgen on the genital ducts of young discoglosses. Early development of seminal vesicles and inhibition of mullerian ducts (author's transl)

Annales d'endocrinologie
D Huchon


Young Discoglossus pictus Otth (Amphibian, Anura) received either male hormone (testosterone or testosterone propionate) or the anti-steroid anti-androgen cyproterone acetate. The male hormone had a masculinizing effect on the genital tract when observed four months later and, paradoxically, the anti-androgen had the same effect: -- Hypertrophy of the posterior segment of the Wolffian ducts yields seminal vesicles, whose wall is covered with a flat epithelium after androgen treatment. Cyproterone acetate treatment, however, results in the cytological differentiation of this epithelium. -- Müllerian ducts persist in a vestigial form. In this respect, the inhibitory action of cyproterone acetate is stronger than that of the male hormone.

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Mentioned in this Paper

Testosterone Measurement
Specimen Type - Genital
Cyproterone, 1alpha,2 alpha,9 beta,10 alpha-Isomer
Discoglossus pictus
Gartner Ducts

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