PMID: 1197945Jun 1, 1975Paper

Action of intercostal muscle afferents on the respiratory rhythm of anesthetized cats

Respiration Physiology
J E Remmers, I Marttila

Abstract

Experiments designed to reveal an action of intercostal afferent stimulation on the rhythm of breathing were carried out on barbiturate-anesthetized, paralyzed cats, ventilated by a positive pressure respirator. Tetanic stimuli were applied to midthoracic, external intercostal nerves of intact animals and of animals displaying an apneustic pattern consequent to vagotomy and pontine lesions. In intact animals, the respiratory rhythm, as indicated by phrenic efferent activity, could be paced by intercostal nerve stimuli when they were timed to occur in a particular relationship to the lung volume cycle. Apparently, the action of the stimuli supplemented the phasic, volume-related afferent input. The response required considerable spatial summation and resulted from the action of intercostal afferents to either shorten inspiration or prolong expiration. These reflex effects could be attributed to activation of group II afferents. Although the actions of these afferents were relatively weak in the intact preparation, they proved potent in terminating an apneustic breath; brief stimuli, if they activated group II afferents, cut short phrenic discharge and initiated an expiratory phase, thereby restoring a reasonably normal respirato...Continue Reading

References

Oct 1, 1970·Respiration Physiology·J E Remmers
Oct 1, 1972·Respiration Physiology·G W Bradley
Apr 1, 1972·The Journal of Physiology·F J Clark, C von Euler
Apr 1, 1969·Acta Physiologica Scandinavica·E E Decima, C von Euler
Jan 1, 1971·Pflügers Archiv : European journal of physiology·E Camporesi, G Sant' Ambrogio
May 1, 1969·Acta Physiologica Scandinavica·E E Decima, C von Euler
Aug 1, 1967·Respiration Physiology·S BlandR M Cherniack

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Citations

Nov 1, 1976·Respiration Physiology·J E RemmersM D Putnam
May 1, 1977·Respiration Physiology·J G ColebatchD I McCloskey
Dec 1, 1979·Respiration Physiology·D F Speck, C L Webber
Feb 1, 1981·Respiration Physiology·D F Speck, C L Webber
Nov 1, 1982·Respiration Physiology·J P Baker, J E Remmers
May 1, 1985·Respiration Physiology·R ShannonB G Lindsey
Apr 1, 1986·Respiration Physiology·D BartlettE J Doll
Oct 1, 1986·Respiration Physiology·D L Woodall, O P Mathew
Jan 1, 1990·Respiration Physiology·E TakahashiE A Phillipson
Nov 1, 1992·Respiration Physiology·D R Karius, A L Kunz
Jun 1, 1983·Brain Research·A J MillerR Silverstein
Jul 3, 2002·Respiratory Physiology & Neurobiology·M H StellaD Bartlett
Jul 21, 1977·The New England Journal of Medicine·A J BergerJ W Severinghaus
Sep 23, 1982·The New England Journal of Medicine·C Roussos, P T Macklem
Mar 1, 1991·Clinical Physiology·J G van den Aardweg, J M Karemaker
Jan 1, 1993·The American Review of Respiratory Disease·D E O'DonnellM Younes
Jun 1, 1979·Journal of Neurosurgery·E A Frost
Aug 8, 2007·Respiratory Physiology & Neurobiology·Anthony F DiMarcoJaroslaw R Romaniuk
Jan 26, 1988·Brain Research·S Kitano, A Komatsu
May 1, 1978·IEEE Transactions on Bio-medical Engineering·M M Grunstein, J Milic-Emili
Nov 1, 2016·American Journal of Respiratory and Critical Care Medicine·Stéphane DelisleKarim Serri
Nov 11, 2016·Journal of Neurophysiology·Sabhya RanaCarlos B Mantilla
Jun 20, 2019·Pediatric Research·Janneke DekkerArjan B Te Pas
Mar 20, 2018·Frontiers in Pediatrics·Sophie J E CramerArjan B Te Pas
Aug 5, 2000·Journal of Applied Physiology·P M SimonJ C Leiter

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