Actionable Adherence Monitoring: Technological Methods to Monitor and Support Adherence to Antiretroviral Therapy

Current HIV/AIDS Reports
Kate M Bell, Jessica E Haberer

Abstract

Current digital technologies are being used for "actionable adherence monitoring"; that is, technologies that can be used to identify episodes of non-adherence to ART in a timely manner such that tailored interventions based on adherence data can be provided when and where they are needed most. Current digital communication technologies used to monitor ART adherence include electronic adherence monitors (EAMs), digital ingestion monitors, cellular phones, and electronic pharmacy refill tracking systems. Currently available real-time adherence monitoring approaches based on cellular technology allow for the delivery of interventions precisely when and where they are needed. Such technology can potentially enable significant efficiency of care delivery and impact on adherence and associated clinical outcomes. Standard digital advances, such as automated reminders in EAM and electronic pharmacy records, may also achieve improvements with relatively lower cost and easier implementation. Future research is needed to improve the functionality of these approaches, with attention paid to system-level issues through implementation science, as well as acceptability and ethical considerations at the individual level.

References

Sep 11, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J H ArnstenE E Schoenbaum
Mar 29, 2007·Journal of General Internal Medicine·Seth C KalichmanMoira O Kalichman
Jul 9, 2010·Lancet·Paul A Volberding, Steven G Deeks
Jul 20, 2011·The New England Journal of Medicine·Myron S CohenUNKNOWN HPTN 052 Study Team
Mar 13, 2012·AIDS and Behavior·Ann Bartley WilliamsJulie A Womack
Apr 11, 2012·British Journal of Clinical Pharmacology·Bernard VrijensUNKNOWN ABC Project Team
Oct 9, 2012·Biomedical Instrumentation & Technology·Mark Cain
Nov 29, 2012·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Catherine OrrellRobin Wood
May 23, 2014·AIDS·Krisda H ChaiyachatiTill Bärnighausen
Jul 30, 2014·IEEE Transactions on Bio-medical Engineering·Hooman HafeziGeorge M Savage
Apr 19, 2015·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Lora L SabinAllen L Gifford
Sep 12, 2015·Journal of General Internal Medicine·Jeffrey I CampbellJessica E Haberer
Oct 12, 2015·Current HIV/AIDS Reports·Kate JongbloedRichard T Lester
Nov 26, 2015·AIDS and Behavior·I Marion de Sumari-de BoerGibson S Kibiki
Nov 20, 2016·The Lancet. HIV·Jessica E Haberer

❮ Previous
Next ❯

Citations

May 7, 2020·Expert Opinion on Drug Safety·Susanne B Haga
Feb 13, 2021·Patient Preference and Adherence·Alisse HannafordHelen Koenig
May 12, 2020·ACS Infectious Diseases·Derin SevenlerRebecca D Sandlin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.