Activation of fibrinolysis by reinfusion of unwashed salvaged blood after total knee arthroplasty

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
Keiji MatsudaHisashi Kurosawa

Abstract

In 19 patients with RA and 20 with OA who underwent autotransfusion with unwashed salvaged blood (USB) after total knee arthroplasty, we performed serial measurement of D-dimer, FgDP, t-PA, and PIC in the plasma and salvaged blood. The PIC level at the completion of salvaged blood transfusion was closely correlated with the volume of USB reinfused in the RA group (p<0.001). The t-PA level of salvaged blood showed a significant positive correlation with the total volume of postoperative drainage in both the RA and OA groups (p<0.05). The increase of total postoperative drainage associated with reinfusion of USB is largely caused by an increase of t-PA in the salvaged blood.

References

Jun 1, 1992·The Journal of Arthroplasty·J W MartinM E Reedy
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Dec 24, 2005·Biomedizinische Technik. Biomedical Engineering·M WojanA Wild
Oct 15, 2008·International Orthopaedics·Keiji MatsudaHisashi Kurosawa

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Citations

Dec 3, 2014·American Journal of Surgery·Hannah B HarrisonDaniel L Dent
Jan 18, 2015·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·P EsnaultE Kaiser
Oct 16, 2015·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Andrew BurlesonWilliam Hopkinson
Jul 25, 2015·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Nil GulerJawed Fareed
May 27, 2014·The Journal of the American Academy of Orthopaedic Surgeons·Brett Russell LevineRachel M Frank
Jul 10, 2018·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Vasileios SoranoglouThomas P Sculco

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