Activation of Salmonella-specific immune responses in the intestinal mucosa

Archivum Immunologiae Et Therapiae Experimentalis
Aparna Srinivasan, S J McSorley

Abstract

The mammalian immune response to Salmonella has long been a subject of scientific study. Indeed, many of the general aspects of bacterial pathogenesis and host immune defense have been well described. However, a lack of clarity remains concerning important aspects of the host immune response to Salmonella, particularly with regard to the induction of an immune response in the intestinal mucosa. A major limitation has been the general lack of knowledge about specific antigenic targets that are recognized by both the innate and adaptive immune response in the intestine. Progress towards the identification of these targets is critical for the development of a detailed model of immunity to Salmonella and will lead to a better understanding of mucosal immune responses to other intracellular pathogens.

Citations

Jul 20, 2012·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Michał ZimeckiMarian L Kruzel
Nov 13, 2012·Microbial Pathogenesis·Shifeng WangRoy Curtiss
Feb 16, 2008·Immunological Reviews·Laura CampisiNicolas Glaichenhaus
Jul 19, 2011·Biological Research for Nursing·Sara KeelingBarbara St Pierre Schneider
Jul 20, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Seung-Joo LeeStephen J McSorley
Sep 1, 2021·Emerging Microbes & Infections·Yuanyuan WangMei Zhang

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