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Active Amyloid-β Vaccination Results in Epigenetic Changes in the Hippocampus of an Alzheimer's Disease-Like Mouse Model

Current Alzheimer Research

Aug 27, 2019

Roy LardenoijeCynthia A Lemere

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Abstract

While evidence accumulates for a role of epigenetic modifications in the pathophysiological cascade of Alzheimer's disease (AD), amyloid-β (Aβ)-targeted active immunotherapy approaches are under investigation to prevent or slow the progression of AD. The impact of Aβ active vaccines on ...read more

Mentioned in this Paper

Immunologic Adjuvants
Alzheimer's Disease
Amyloid
Biological Markers
Brain
Carrier Proteins
Cognition
Genome
Hippocampus (Brain)
Immunization
2
1
4
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Active Amyloid-β Vaccination Results in Epigenetic Changes in the Hippocampus of an Alzheimer's Disease-Like Mouse Model

Current Alzheimer Research

Aug 27, 2019

Roy LardenoijeCynthia A Lemere

PMID: 31453788

DOI: 10.2174/1567205016666190827122009

Abstract

While evidence accumulates for a role of epigenetic modifications in the pathophysiological cascade of Alzheimer's disease (AD), amyloid-β (Aβ)-targeted active immunotherapy approaches are under investigation to prevent or slow the progression of AD. The impact of Aβ active vaccines on ...read more

Mentioned in this Paper

Immunologic Adjuvants
Alzheimer's Disease
Amyloid
Biological Markers
Brain
2
1
4

Similar Papers Found In These Feeds

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Paper Details
References
  • References35
  • Citations
1234
  • References35
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    No citations available

    This paper may not have been cited yet.

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