PMID: 6412970Jul 1, 1983Paper

Active and passive immunization against Pseudomonas aeruginosa infection of burned patients

Burns, Including Thermal Injury
E A Roe, R J Jones

Abstract

A 16-part polyvalent pseudomonas vaccine, PEV-01 and an immunoglobulin prepared from plasma from human volunteers vaccinated with PEV-01 were tested in a controlled clinical trial in burned patients at Safdarjang hospital, New Delhi. The mortality of the burned patients was reduced four-fold in adults and three-fold in children by the immunological treatments. Both immunoglobulin and vaccine increased the concentration of protective antibody. Patients responded to all 16 components in PEV-01. The vaccine caused no toxic side-effects and enhanced the bactericidal activity of polymorphonuclear leucocytes against Pseudomonas aeruginosa.

References

Aug 1, 1969·Archives of Surgery·J W AlexanderW A Altemeier

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Citations

Apr 29, 2005·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Robert L Sheridan
Dec 1, 1992·Burns : Journal of the International Society for Burn Injuries·O A AtoyebiT Odugbemi
Jun 9, 2020·Current Problems in Surgery·Elizabeth BlearsDavid N Herndon

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