Active colloids as mobile microelectrodes for unified label-free selective cargo transport

Nature Communications
Alicia BoymelgreenGilad Yossifon

Abstract

Utilization of active colloids to transport both biological and inorganic cargo has been widely examined in the context of applications ranging from targeted drug delivery to sample analysis. In general, carriers are customized to load one specific target via a mechanism distinct from that driving the transport. Here we unify these tasks and extend loading capabilities to include on-demand selection of multiple nano/micro-sized targets without the need for pre-labelling or surface functionalization. An externally applied electric field is singularly used to drive the active cargo carrier and transform it into a mobile floating electrode that can attract (trap) or repel specific targets from its surface by dielectrophoresis, enabling dynamic control of target selection, loading and rate of transport via the electric field parameters. In the future, dynamic selectivity could be combined with directed motion to develop building blocks for bottom-up fabrication in applications such as additive manufacturing and soft robotics.

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Citations

Aug 4, 2018·Soft Matter·Ran Niu, Thomas Palberg
Mar 28, 2020·Micromachines·Chong ShenH Daniel Ou-Yang
Aug 31, 2020·Light, Science & Applications·Xiaolei PengYuebing Zheng
Nov 28, 2019·Physical Review. E·Laida Rodríguez-SánchezPablo García-Sánchez
Apr 20, 2019·Physical Review. E·J E Flores-MenaAntonio Ramos
Sep 25, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Luisa SonntagVeronika Magdanz
Feb 1, 2019·Micromachines·Pablo García-SánchezAntonio Ramos
Jul 7, 2019·Micromachines·Kai DuYukun Ren
Feb 2, 2021·Chemical Reviews·Fernando SotoJoseph Wang
Feb 9, 2021·Nano Letters·Huan WangHong-Bo Sun
Dec 12, 2020·Journal of Colloid and Interface Science·Sinwook ParkGilad Yossifon
Nov 12, 2020·Advanced Science·Fernando SotoUtkan Demirci
Aug 27, 2019·Journal of the American Chemical Society·Zuochen WangYufeng Wang
Mar 20, 2019·ACS Applied Materials & Interfaces·Xueqing ZhangHuangxian Ju
Aug 18, 2021·Light, Science & Applications·Xiaolei PengYuebing Zheng
Mar 7, 2020·ACS Sensors·Sinwook Park, Gilad Yossifon
Dec 6, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Xiaoye HuoGilad Yossifon
Sep 18, 2021·Proceedings of the National Academy of Sciences of the United States of America·Yue WuGilad Yossifon
Oct 6, 2021·Soft Matter·Behrouz BehdaniCarlos A Silvera Batista

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Methods Mentioned

BETA
electrophoresis

Software Mentioned

COMSOL
Matlab
Image J

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