Active gastrointestinal bleeding: evaluation with contrast-enhanced ultrasonography

Abdominal Imaging
Noriaki ManabeHiroaki Kusunoki

Abstract

Advances in contrast-enhanced ultrasonography (CEUS) have made it possible to detect leakage of contrast medium. The aim of the present study was to prospectively evaluate the efficacy of CEUS for depiction of active gastrointestinal (GI) bleeding. Eighty-nine patients (50 men and 39 women with a mean age of 68.6 years) who had evidence of GI bleeding were enrolled. After injection of Sonazoid, CEUS was performed for 2 min. Evidence of active GI bleeding was defined as positive when pooling or leakage of contrast medium was observed in the GI tract. Calculation of the sensitivity, specificity, positive and negative predictive values, and the positive and negative likelihood ratio (LR) for depiction of active GI bleeding by CEUS was done by comparison with GI endoscopy. The sensitivity, specificity, positive predictive value, and negative predictive value of CEUS for detection of active GI bleeding were 73.7% (95% CI: 48.8, 90.9), 97.1% (95% CI: 90.0, 99.7), 87.5% (95% CI: 61.7, 98.4), and 93.2% (95% CI: 84.7, 97.7), respectively. The positive LR and negative LR were 25.4 and 0.27, respectively. CEUS is highly effective for the detection of active GI bleeding.

References

Aug 17, 1974·Lancet·J A ForrestD J Shearman
Jul 1, 1997·Diseases of the Colon and Rectum·A M VernavaF E Johnson
Oct 15, 1998·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·B B GoldbergF Forsberg
Dec 16, 1998·Gastrointestinal Endoscopy·G R Zuckerman, C Prakash
Oct 29, 2000·The American Journal of Gastroenterology·R S BloomfeldD C Rockey
Aug 22, 2002·Academic Radiology·A BauerN Weissman
May 20, 2003·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Orlando CatalanoAlfredo Siani
Nov 19, 2003·Annals of Internal Medicine·Alan BarkunUNKNOWN Nonvariceal Upper GI Bleeding Consensus Conference Group
Dec 10, 2003·Radiologic Clinics of North America·Koenraad J MortelePablo R Ros
May 6, 2004·Scandinavian Journal of Gastroenterology·K KunihiroK Chayama
Jul 26, 2005·Radiology·Jiro HataHiroaki Kusunoki
Oct 26, 2005·Gastrointestinal Endoscopy·Raquel E DavilaUNKNOWN Standards of Practice Committee
Dec 1, 2005·Abdominal Imaging·O CatalanoA Siani
Apr 14, 2006·Alimentary Pharmacology & Therapeutics·T YamaguchiK Chayama
Sep 1, 2006·Journal of Clinical Ultrasound : JCU·Hiroko NaganumaKayoko Furukawa
Oct 22, 2008·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jackson D HamiltonO Clark West
Dec 23, 2008·AJR. American Journal of Roentgenology·Siarhei KuzmichTatsiana Kuzmich

❮ Previous
Next ❯

Citations

Sep 1, 2011·Abdominal Imaging·Carlos Nicolau, Tomás Ripollés
Sep 20, 2011·Radiología·S Quiroga GómezJ Castell Conesa
Nov 13, 2013·Interactive Cardiovascular and Thoracic Surgery·Koji NakanishiMikizo Nakai
Dec 3, 2014·La Radiologia medica·Roberto FarinaLuigia Romano
Mar 4, 2020·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Christopher D MaloneRaja S Ramaswamy
Nov 18, 2020·Scandinavian Journal of Gastroenterology·Minoru FujitaKen Haruma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Radiographics : a Review Publication of the Radiological Society of North America, Inc
Bruno M GraçaFilipe Caseiro-Alves
Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association
Lisa L Strate, Christopher R Naumann
© 2022 Meta ULC. All rights reserved