Active remote-site musculoskeletal infection as a risk factor for periprosthetic infection in a new joint implant: A case series

Annals of Medicine and Surgery
Bassem I HaddadElsiddig E Mahmoud

Abstract

Arthroplasty has always been associated with complications, such as the possibility of periprosthetic infection. The presence of an active infection at the site of the planned surgery is considered a contraindication for the new implant. However, it is unclear whether there is an association between the presence of remote musculoskeletal infection and the development of infection in the prosthetic joint itself. We report six cases involving patients with active ongoing musculoskeletal infections at a remote site who underwent arthroplasty. Four male and two female patients were included in this review. Three patients underwent total hip arthroplasty, one underwent hip hemiarthroplasty, and two underwent total knee arthroplasty. All surgeries were performed in the presence of different stages of infection at a remote site; two had active infections with pus-discharging sinus, one was being treated with long-term oral antibiotic suppression, and three patients were diagnosed with remote prosthetic joint infections on the basis of joint aspiration or intraoperative cultures. Clinical assessments of pain, wound erythema or drainage, and soft tissue swelling were performed at follow-up. Radiography and analysis of inflammatory marke...Continue Reading

References

Oct 16, 2004·The New England Journal of Medicine·Werner ZimmerliPeter E Ochsner
Jun 23, 2006·Drugs·Andrej Trampuz, Werner Zimmerli
Dec 29, 2007·Journal of Orthopaedic Surgery·C T LimK C Ang
Nov 15, 2008·Clinical Orthopaedics and Related Research·Panagiotis KoulouvarisNigel E Sharrock
Feb 26, 2009·Clinical Orthopaedics and Related Research·Elie GhanemJavad Parvizi
Mar 24, 2010·Clinical Orthopaedics and Related Research·Dann J LaudermilchRichard L McGough
Dec 2, 2010·The Journal of the American Academy of Orthopaedic Surgeons·Javad Parvizi, Craig J Della Valle
Jun 15, 2011·The Journal of Infection·Parham SendiWerner Zimmerli
Mar 6, 2012·The Journal of Arthroplasty·S Mehdi JafariPeter F Sharkey
Apr 12, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ricardo SousaAndrea Guyot
Sep 4, 2015·The Journal of Bone and Joint Surgery. American Volume·Hilal Maradit KremersDaniel J Berry
Nov 13, 2015·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·David Martínez-VélezJosé Cordero-Ampuero
Jun 2, 2017·World Journal of Orthopedics·David A GeorgeCarlo L Romano

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray
total hip arthroplasty
total hip prosthesis
ESR

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.