Activities of mitochondrial aspartate aminotransferase and creatine kinase isoenzyme MB in serum following coronary bypass surgery

Clinica Chimica Acta; International Journal of Clinical Chemistry
N E HusebyJ Vaage

Abstract

The mitochondrial isoenzyme of aspartate aminotransferase showed only slight increases in serum of twenty-seven patients after uncomplicated coronary bypass surgery, which contrasted the rapid and substantial increases in creatine kinase MB. In seven patients suffering perioperative infarction or serious complications, substantial increases in mitochondrial aspartate aminotransferase were detected and the elevations in creatine kinase MB were prolonged. Mitochondrial aspartate aminotransferase may appear as a specific marker of myocardial necrosis following coronary bypass surgery. The elevations of creatine kinase and creatine kinase MB were detected as early as 5 minutes after onset of coronary reperfusion and slightly higher activities were measured in coronary sinus blood than in systemic blood sampled simultaneously. Increases in mitochondrial aspartate aminotransferase, however, could first be measured 8 hours after reperfusion.

References

Apr 29, 1988·Clinica Chimica Acta; International Journal of Clinical Chemistry·W T HermensG J van der Vusse
Jan 1, 1986·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·G J van der VusseR S Reneman
Apr 30, 1986·Clinica Chimica Acta; International Journal of Clinical Chemistry·J E DevineJ E Codd
Aug 31, 1984·Clinica Chimica Acta; International Journal of Clinical Chemistry·S Y FarahR N Sapsford
Jan 1, 1983·Scandinavian Journal of Thoracic and Cardiovascular Surgery·S LindalL Jørgensen
Apr 27, 1984·Clinica Chimica Acta; International Journal of Clinical Chemistry·S W Rabkin, P Desjardins
Apr 1, 1984·Journal of Molecular and Cellular Cardiology·H M PiperP G Spieckermann

❮ Previous
Next ❯

Citations

Jan 1, 1994·Scandinavian Journal of Thoracic and Cardiovascular Surgery·M J HippeläinenK T Huttunen
Jan 1, 1994·Scandinavian Journal of Thoracic and Cardiovascular Surgery·G KällnerA Kallner

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinica Chimica Acta; International Journal of Clinical Chemistry
W T HermensG J van der Vusse
Clinica Chimica Acta; International Journal of Clinical Chemistry
P MairB Puschendorf
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
U HakeH Oelert
© 2021 Meta ULC. All rights reserved