Activity of fin muscles and fin motoneurons during swimming motor pattern in the lamprey

The European Journal of Neuroscience
Tim MentelAnsgar Büschges

Abstract

Coordination of motoneuron activity is a fundamental prerequisite for the generation of functional locomotor patterns. We investigate the neural mechanisms that coordinate activity of motoneuron pools in the vertebrate spinal cord with differing phases of activity in the locomotor cycle in a simple motor system, the lamprey swimming network. In the region of dorsal fins the lamprey spinal cord contains two groups of motoneurons: the myotomal motoneurons that innervate the trunk muscles; and the fin motoneurons controlling muscle fibres of the dorsal fins. We investigated the activity of fin muscles during swimming in vivo and that of fin motoneurons during fictive swimming in vitro. During swimming in vivo with cycle periods of 4-8 Hz, fin muscle activity covered a broad portion of the cycle, with the peak of activity out-of-phase to the ipsilateral myotomal muscles. During fictive swimming evoked by N-methyl-d-aspartate in the isolated spinal cord, fin motoneurons expressed similar out-of-phase activity. The phase relationship of the synaptic drive to fin motoneurons was examined by recording their activity intracellular during fictive swimming. Three different forms of membrane potential oscillation with different time course...Continue Reading

References

Jul 1, 1992·The Journal of Comparative Neurology·O ShupliakovS Grillner
Jun 1, 1991·Journal of Applied Physiology·R R RoyV R Edgerton
Jan 12, 1988·Brain Research·J T Buchanan, S Grillner
Nov 1, 1971·Journal of Neurophysiology·K L Birnberger, C M Rovainen
Mar 15, 1974·The Journal of Comparative Neurology·C M Rovainen
Nov 1, 1971·Journal of Neurophysiology·C M Rovainen, K L Birnberger
Feb 3, 1984·Science·S GrillnerP A Lagerbäck
Mar 4, 1982·Brain Research·S GrillnerK Sigvardt
Jan 1, 1995·Journal of Neurophysiology·J T Buchanan, S Kasicki
Jan 1, 1993·Annual Review of Neuroscience·K G Pearson
Jun 10, 1996·The Journal of Comparative Neurology·A el ManiraS Grillner
Dec 31, 1998·Current Microbiology·Y NitzanI Pechatnikov
Jun 9, 2000·Annual Review of Physiology·K G Pearson
Feb 19, 2003·Brain Research. Brain Research Reviews·Sten Grillner, Peter Wallén
Mar 4, 2003·Journal of Neurophysiology·Lorenzo Cangiano, Sten Grillner
Jul 3, 2003·Nature Reviews. Neuroscience·Sten Grillner
Dec 5, 2003·Progress in Brain Research·Keir G Pearson
Feb 14, 2004·The Journal of Organic Chemistry·Bernd SchmidtBurkhard Costisella
Feb 18, 2004·Molecular & Cellular Proteomics : MCP·Elizabeth PohlerTed R Hupp
Jan 28, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Lorenzo Cangiano, Sten Grillner
Feb 1, 2002·Integrative and Comparative Biology·Paul W Webb

❮ Previous
Next ❯

Citations

Feb 14, 2012·Journal of Neural Engineering·K A MazurekV K Mushahwar
May 2, 2009·Journal of Communication Disorders·Meredith E Estep
Sep 5, 2009·The Journal of Comparative Neurology·Carlos Ernesto RestrepoOle Kiehn
Nov 26, 2010·Progress in Neurobiology·Olivia J MullinsW Otto Friesen
Sep 13, 2019·Physiological Reviews·Sten Grillner, Abdeljabbar El Manira
Jun 2, 2021·Scientific Reports·Heiko StarkEmanuel Andrada

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.