Activity of mitomycin C, other antibiotics, and serum against lysogenic bacteria.

Journal of Bacteriology
L H Muschel, K Schmoker

Abstract

Muschel, Louis H. (University of Minnesota, Minneapolis), and Karen Schmoker. Activity of mitomycin C, other antibiotics, and serum against lysogenic bacteria. J. Bacteriol. 92:967-971. 1966.-Lysogenic bacteria were found to be more sensitive to the bactericidal action of mitomycin C or streptonigrin than the corresponding sensitive or indicator strains. This result may be attributed to the induction of phage production in lysogenic cells by these antibiotics. Lysogenic and sensitive bacteria were, however, equally sensitive to chloramphenicol, streptomycin, and polymyxin B. In contrast to their greater sensitivity to certain phage-inducing antibiotics, the lysogenic state resulted in greater resistance to the bactericidal reaction of serum mediated by the complement system. In general, therefore, the lysogenic state may result in either decreased or increased sensitivity to various antimicrobial agents.

Citations

Aug 1, 1990·Oral Microbiology and Immunology·R H StevensD H Fine
Dec 1, 1968·Journal of Bacteriology·L H MuschelL S Baron
Nov 1, 1970·Applied Microbiology·E B Lillehoj, A Ciegler

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.