PMID: 8610098Apr 2, 1996Paper

Activity of primate inferotemporal neurons related to a sought target in pair-association task

Proceedings of the National Academy of Sciences of the United States of America
Yuji NayaY Miyashita

Abstract

Visual long-term memory in primates has been assessed by using the pair-association (PA) task, in which a subject retrieves and chooses the paired associate of a cue picture. Our previous studies on single neurons in the anterior inferotemporal (AIT) cortex suggested their roles in representing paired associates in the mind. To test the possibility that the delay activity of AIT neurons is related to a particular picture as a sought target, we devised the PA with color switch (PACS) task. In the PACS task, the necessity for memory retrieval and its initiation time were controlled by a color switch in the middle of the delay period. A control task, in which there is no color switch, corresponds to the conventional delayed matching-to-sample (DMS) task where the monkey chooses the same picture as a cue. We found that AIT neurons started to respond just after the color switch in the PACS task, when the cue-optimal picture's associate was presented as a cue. In contrast, they showed no response change in the DMS task. We confirmed that this effect is not due to the visual response to colors. Furthermore, when the cue-optimal picture was presented as a cue, these neurons showed suppression after the color switch in the PACS task. Th...Continue Reading

References

Dec 1, 1991·Visual Neuroscience·J H MaunsellD D DePriest
Sep 20, 1991·Science·L R Squire, S Zola-Morgan
Jul 1, 1994·Trends in Neurosciences·K Sakai, Y Miyashita
Mar 21, 1994·Neuroreport·K Sakai, Y Miyashita

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Citations

Sep 15, 2005·Experimental Brain Research·Gustavo DecoJoaquín Fuster
Apr 6, 2013·Biological cybernetics·Christian R Huyck, Peter J Passmore
May 21, 2013·Journal of Physiology, Paris·Shintaro Funahashi, Jorge Mario Andreau
Jun 10, 1998·Progress in Neurobiology·M W Brown, J Z Xiang
Oct 6, 1998·Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie·Y MiyashitaH Tomita
Apr 18, 2002·Brain Research. Cognitive Brain Research·Masahiko Morita, Atsuo Suemitsu
Feb 7, 2001·Current Opinion in Neurobiology·Y Miyashita, T Hayashi
Nov 24, 2007·Cerebral Cortex·Reza Habib, Lars Nyberg
Mar 15, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Takahiro OsadaYasushi Miyashita
Mar 15, 2008·Science·Gianluigi MongilloMisha Tsodyks
Nov 15, 2003·Journal of Cognitive Neuroscience·Tjeerd Jellema, David I Perrett
Nov 20, 2008·Journal of Cognitive Neuroscience·Nicolas Brunel, Frédéric Lavigne
May 1, 2010·Journal of Cognitive Neuroscience·Frédéric LavigneNelly Darmon
Apr 11, 2006·PLoS Computational Biology·Thomas Gisiger, Michel Kerszberg
Mar 12, 2010·PloS One·Masahiko MoritaHiromi Morita
May 1, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Luke Woloszyn, David L Sheinberg
Aug 5, 2014·PloS One·Yangyang ZhangXianchun Li
Mar 26, 2003·Proceedings of the National Academy of Sciences of the United States of America·Masatoshi YoshidaYasushi Miyashita
Sep 27, 2001·Proceedings of the National Academy of Sciences of the United States of America·A MessingerT D Albright
Jul 18, 2014·Annual Review of Neuroscience·Wendy A Suzuki, Yuji Naya
Jun 28, 2005·The European Journal of Neuroscience·Gianluigi MongilloDaniel J Amit
Nov 19, 2003·The European Journal of Neuroscience·Gianluigi MongilloNicolas Brunel
Dec 6, 2003·The European Journal of Neuroscience·Yuji NayaYasushi Miyashita
Aug 26, 2006·The European Journal of Neuroscience·Verónica NácherCarlos Acuña
Apr 11, 2012·The European Journal of Neuroscience·Xiaochuan Pan, Masamichi Sakagami
May 16, 2015·Neuroscience and Biobehavioral Reviews·Nikolaos C Aggelopoulos
Mar 6, 2009·Current Opinion in Neurobiology·Richard Passingham
Feb 13, 2001·Current Biology : CB·S P Gandhi
Jan 15, 2013·Neuron·Jamie K FitzgeraldJohn A Assad
Apr 29, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Friedemann Pulvermüller, Max Garagnani
Oct 1, 1998·Neurobiology of Learning and Memory·Y MiyashitaT Fukushima
Feb 7, 2015·Frontiers in Psychology·Elisa M TartagliaNicolas Brunel

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