PMID: 7066690Mar 25, 1982

Activity of primate precentral neurons during voluntary movements triggered by visual signals

Brain Research
J T MurphyY C Wong

Abstract

Awake, intact monkeys were trained to perform discrete flexion or extension movements of the hand about the wrist in response to visual signals. The object of the movement was to align a cursor, coupled to a manipulandum, on a target line. Cursor and target lines are displayed on a video monitor placed in front of the monkey. The target line was stepped to the right or left, randomly with regard to direction and timing, with each step implying an instruction for the monkey to make a voluntary movement for alignment. Single unit recording was made in the forelimb area of contralateral precentral cortex. Neurons were classified by their responses to passive sensory stimulation and the effects of local intracortical microstimulation into two populations; wrist flexion-extension (F-E) neurons, and all other forelimb neurons (non-wrist (F-E)). A significantly higher proportion of wrist (F-E) neurons as compared to non-wrist (F-E) neurons were task-related. Moreover the wrist (F-E) neurons exhibited exclusively reciprocal responses to the oppositely directed visual signals, whereas the non-wrist (F-E) neurons showed both reciprocal and bidirectional responses. No significant differences in mean latencies of responses, either in respe...Continue Reading

References

Oct 13, 1978·Brain Research·P L Strick, J B Preston
Mar 1, 1979·Brain Research Bulletin·I Hamada, K Kubota
Feb 1, 1979·Canadian Journal of Physiology and Pharmacology·Y C WongJ T Murphy
Dec 1, 1975·Journal of Neurology, Neurosurgery, and Psychiatry·M HallettR R Young
Aug 1, 1974·Physiology & Behavior·J T MurphyY C Wong
Sep 25, 1954·Nature·H J HUFSCHMIDT, T HUFSCHMIDT

Citations

Jan 1, 1984·Experimental Brain Research·M D Crutcher, M R DeLong
Nov 30, 2012·Experimental Brain Research·M EdwardsonE E Fetz
Jun 1, 1987·Behavioural Brain Research·W A MacKay, D J Crammond
Sep 16, 1985·Brain Research·H C KwanY C Wong
Oct 1, 1994·Journal of Child Neurology·A K Afifi
Mar 11, 2003·Nature Neuroscience·Kan Singh, Stephen H Scott
Feb 1, 1985·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·J T MurphyY C Wong
Feb 1, 1985·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·J T MurphyY C Wong

Related Concepts

Upper Arm
Functional Cerebral Localization
Macaca
Motor Cortex
Reaction Time
Visual Perception
Wrist

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