Activity of telavancin compared to other agents against coagulase-negative staphylococci with different resistotypes by time kill

Diagnostic Microbiology and Infectious Disease
Gengrong LinKlaudia Kosowska-Shick

Abstract

Among 10 coagulase-negative staphylococci, telavancin, quinupristin/dalfopristin, and tigecycline were the most potent antimicrobials. Telavancin exhibited bactericidal effect to 9 strains out of 10 tested at 4× MIC after 24 h of exposure similar to those of vancomycin and daptomycin. By contrast, linezolid was mainly bacteriostatic and teicoplanin was bactericidal to 7 strains tested at 4× MIC after 24 h.

References

Nov 24, 1999·São Paulo Medical Journal = Revista Paulista De Medicina·E C MintoA da Costa Darini
Mar 8, 2003·Journal of Clinical Microbiology·Adriana N De PaulisJorge E Santoianni
May 5, 2006·Journal of Clinical Microbiology·François TruebaOlivier Chesneau
Oct 17, 2007·Annual Review of Medicine·A Simon Lynch, Gregory T Robertson
Apr 30, 2008·Antimicrobial Agents and Chemotherapy·Kevin M KrauseBret M Benton
Feb 18, 2010·Antimicrobial Agents and Chemotherapy·Gengrong LinPeter C Appelbaum
Aug 24, 2010·Diagnostic Microbiology and Infectious Disease·Klaudia Kosowska-ShickCynthia J Whitener

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