Acute acalculous cholecystitis with eosinophilic infiltration

Pediatrics International : Official Journal of the Japan Pediatric Society
Yuki MutaEiichi Arai

Abstract

We report a case of acute acalculous cholecystitis with eosinophilic infiltration. A previously healthy 6-year-old boy was referred with right abdominal pain. Imaging demonstrated marked thickening of the gallbladder wall and peri-cholecystic effusion. Acute acalculous cholecystitis was diagnosed. Symptoms persisted despite conservative treatment, therefore cholecystectomy was performed. Pathology indicated infiltration of eosinophils into all layers of the gallbladder wall. The postoperative course was uneventful and the patient has had no further symptoms. Eosinophilic cholecystitis is acute acalculous cholecystitis with infiltration of eosinophils. The causes include parasites, gallstones, allergies, and medications. In addition, it may be seen in conjunction with eosinophilic gastroenteritis, eosinophilic pancreatitis, or both. An allergic reaction to abnormal bile is thought to be the underlying cause. The present case did not fulfill the diagnostic criteria of eosinophilic cholecystitis, but this may have been in the process of developing.

References

May 1, 1993·The American Journal of Surgical Pathology·D J Dabbs
Jan 10, 2002·Journal of Pediatric Surgery·Mustafa ImamoğluAli Ahmetoğlu
Sep 19, 2007·Pediatrics International : Official Journal of the Japan Pediatric Society·Youn Ho ShinMyung Jun Kim

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Citations

Nov 30, 2018·World Journal of Gastroenterology : WJG·Dimitri Poddighe, Vitaliy Sazonov
Jul 7, 2020·Journal of Pediatric Surgery·Luz Nélida Garzón GEdna Margarita Quintero C

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