Acute and intermediate-term clinical outcomes following Heparin coated BX coronary stent implantation in patients with thrombus containing lesions

International Journal of Cardiovascular Interventions
Jyotsna MadduriRan Kornowski

Abstract

Coronary stenting in acute coronary syndromes might be associated with increased procedural complications and stent thrombosis risk. Heparin-coated stent (HCS) may improve procedural outcomes when treating these high-risk lesions. The purpose of this study was to determine the safety and efficacy of HCS in patients with acute coronary syndromes and thrombus containing lesions. Between January 2001 and January 2002, 49 patients (42 male) with thrombus containing lesions (32 sustained acute myocardial infarction) received HC BX stents (HepaCoat) at our hospital. Procedural, hospital and six-month outcomes and quantitative angiographic analysis data were obtained from all patients. The mean age of patients was 58 +/- 14 years, 45% had multi-vessel disease and 24% were diabetics. Fifteen patients (31%) received a second HCS for sub-optimal results or threatened closure. Procedural success was achieved in 94% of patients. The mean stent diameter and length was 3.2 +/- 0.2 mm and 18.2 +/- 7.4 mm. The mean TIMI flow increased from 1.3 +/- 1.3 to 2.9 +/- 0.3 and the mean diameter stenosis before and after intervention was 84 +/- 21% and 12 +/- 14%. In-hospital and 30-day follow-up were eventually without occurrence of death, myocardial...Continue Reading

References

Oct 1, 1995·Circulation Research·G Fager
Sep 1, 1994·Catheterization and Cardiovascular Diagnosis·P H Wong, C M Wong
Feb 11, 1999·Journal of the American College of Cardiology·R KornowskiM B Leon
Feb 9, 2002·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Fenwei WangBarry F Uretsky
Jun 11, 2002·Journal of Interventional Cardiology·C BickelJ Meyer
Nov 13, 2002·Journal of the American College of Cardiology·James L OrfordPeter B Berger

❮ Previous
Next ❯

Citations

Apr 7, 2006·Vascular and Endovascular Surgery·David R Whittaker, Mark F Fillinger

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.